{"id":"W1995602800","doi":"10.1155/2011/808967","title":"Protective Effects of Liposomal N-Acetylcysteine against Paraquat-Induced Cytotoxicity and Gene Expression","year":2011,"lang":"en","type":"article","venue":"Journal of Toxicology","topic":"Paraquat toxicity studies and treatments","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Lakehead University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cytotoxicity; Acetylcysteine; Paraquat; Pharmacology; Reactive oxygen species; Liposome; Intracellular; Glutathione; Viability assay; Antioxidant; Chemistry; Superoxide dismutase; Cytoprotection; Oxidative stress; Biochemistry; Apoptosis; Biology; In vitro; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000245333,0.0002962773,0.0002987786,0.0001659011,0.000135304,0.0002597064,0.0001742844,0.0002656119,0.0007993958],"category_scores_gemma":[0.0002487632,0.0001008303,0.0001729208,0.00009100021,0.0003160037,0.0003687367,0.0001899449,0.0002733352,0.0001714713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001892028,"about_ca_system_score_gemma":0.0002200568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005384266,"about_ca_topic_score_gemma":0.0004623823,"domain_scores_codex":[0.9998997,0.00003109697,0.00001131541,0.00001918293,0.00001986943,0.00001873928],"domain_scores_gemma":[0.9998637,0.00003073622,0.00003415313,0.00001668535,0.00003184569,0.00002282305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003025513,0.0000532233,0.00007665587,0.0000633333,0.000006081488,0.0000300905,0.00002006089,0.00004910563,0.9979951,0.00006006119,0.00001386543,0.001329904],"study_design_scores_gemma":[0.00003988118,0.00112018,0.0008685111,0.000009382613,0.00002169713,0.0001002842,0.00002808055,0.000486518,0.9965862,0.00003646405,0.0006988433,0.000003891023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954639,0.002277231,0.001502103,0.00008835441,0.00002145401,0.00003652187,0.00007389211,0.0000317312,0.0005046434],"genre_scores_gemma":[0.9969379,0.0008739657,0.001392399,0.00004499184,0.000008352576,0.00002475152,0.0001120291,0.000008313738,0.0005973654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007993958,"threshold_uncertainty_score":0.002674222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03208707473913325,"score_gpt":0.2778026061520397,"score_spread":0.2457155314129065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}