{"id":"W1995602800","doi":"10.1155/2011/808967","title":"Protective Effects of Liposomal N-Acetylcysteine against Paraquat-Induced Cytotoxicity and Gene Expression","year":2011,"lang":"en","type":"article","venue":"Journal of Toxicology","topic":"Paraquat toxicity studies and treatments","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Lakehead University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cytotoxicity; Acetylcysteine; Paraquat; Pharmacology; Reactive oxygen species; Liposome; Intracellular; Glutathione; Viability assay; Antioxidant; Chemistry; Superoxide dismutase; Cytoprotection; Oxidative stress; Biochemistry; Apoptosis; Biology; In vitro; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002061151,0.0001938115,0.0008031219,0.0001710391,0.00006909976,0.000003111875,0.00008804867,0.0001882183,0.00001434783],"category_scores_gemma":[0.000345085,0.000136814,0.0001580619,0.0001087357,0.0001170081,0.00008872438,0.00008686263,0.0002850283,0.000003875162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008851202,"about_ca_system_score_gemma":0.00008829898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001757896,"about_ca_topic_score_gemma":0.000009729608,"domain_scores_codex":[0.9986864,0.0001475412,0.000513368,0.0001798342,0.0002205677,0.000252265],"domain_scores_gemma":[0.9987028,0.0001469072,0.0006049642,0.0001704978,0.0001791807,0.0001956461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001697002,0.001103456,0.01463694,0.0001537824,0.0005253417,0.0007279984,0.0009042931,8.756974e-7,0.9782549,0.0000167239,0.00006925243,0.001909436],"study_design_scores_gemma":[0.005526027,0.00898873,0.1224556,0.0002385185,0.0002224574,0.0006309203,0.00009622595,0.00001472265,0.8616101,0.0001032128,0.0000192566,0.00009424713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973673,0.0007778507,0.000371746,0.0001566987,0.0002185838,0.0006155742,0.000002781045,0.000009921816,0.0004795672],"genre_scores_gemma":[0.9961888,0.0001541058,0.00328576,0.0001572173,0.0001403234,0.00001820939,6.164007e-7,0.00001626048,0.00003872337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1166448,"threshold_uncertainty_score":0.5579115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03208707473913325,"score_gpt":0.2778026061520397,"score_spread":0.2457155314129065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}