{"id":"W1995620440","doi":"10.1016/j.cgh.2005.11.013","title":"Oral p38 Mitogen-Activated Protein Kinase Inhibition With BIRB 796 for Active Crohn’s Disease: A Randomized, Double-Blind, Placebo-Controlled Trial","year":2006,"lang":"en","type":"article","venue":"Clinical Gastroenterology and Hepatology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Crohn's disease; Internal medicine; Placebo; Adverse effect; Gastroenterology; Clinical endpoint; Inflammatory bowel disease; C-reactive protein; Clinical trial; Disease; Pathology; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008448657,0.0004104835,0.001201049,0.0001038928,0.0001864677,0.00002743894,0.0001488222,0.000524573,0.00003314939],"category_scores_gemma":[0.0003618747,0.0003255861,0.0005116272,0.00004536261,0.001215241,0.00001625217,0.0001092667,0.0002985358,0.00000643238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002136304,"about_ca_system_score_gemma":0.0002441817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002643245,"about_ca_topic_score_gemma":0.0005013029,"domain_scores_codex":[0.9961609,0.001180099,0.001012661,0.0008980313,0.0001143285,0.0006339293],"domain_scores_gemma":[0.9983723,0.0002074233,0.0005163768,0.0003809718,0.0002206335,0.0003023141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9807914,0.0007400081,0.01448887,0.00004037789,0.0005371748,0.0002677162,0.000007088582,0.00001176368,0.002031419,0.0004497066,0.0005483063,0.00008620993],"study_design_scores_gemma":[0.9875787,0.00244762,0.006962239,0.00001975261,0.0005182851,0.00003035453,0.00001144899,0.0001700701,0.001068648,0.0004414393,0.0005081483,0.0002432634],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882739,0.00009067858,0.002370785,0.0006577455,0.0004324947,0.007993433,0.00008338981,0.00004385853,0.00005374714],"genre_scores_gemma":[0.9920743,0.00002031346,0.0003790375,0.0007521336,0.0006137457,0.005238313,0.0005587029,0.00004655641,0.0003168797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007526626,"threshold_uncertainty_score":0.9999196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02022092141758378,"score_gpt":0.2999335686349988,"score_spread":0.2797126472174151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}