{"id":"W1995626255","doi":"10.1016/s0197-0186(03)00065-2","title":"Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy","year":2003,"lang":"en","type":"article","venue":"Neurochemistry International","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Saint-Luc","funders":"","keywords":"Neuroactive steroid; GABAA receptor; Benzodiazepine; Hepatic encephalopathy; Coupling (piping); Allopregnanolone; Neuroscience; Pharmacology; Receptor; Chemistry; Medicine; Biology; Internal medicine; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002037051,0.0003081797,0.0003599594,0.0006338267,0.0003862458,0.0002436925,0.0002378865,0.0002885908,0.001753617],"category_scores_gemma":[0.001082869,0.0002606535,0.0001270687,0.0002621766,0.00118243,0.0003804887,0.0002778283,0.0004728907,0.0002247774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003739979,"about_ca_system_score_gemma":0.0001928462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001538478,"about_ca_topic_score_gemma":0.0009122685,"domain_scores_codex":[0.9998683,0.00004374078,0.00001353833,0.00001819035,0.00002225697,0.00003386747],"domain_scores_gemma":[0.999611,0.0001748252,0.00005369024,0.00005700686,0.00004142013,0.00006204043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.030262,0.0004500493,0.1062623,0.0002997112,0.0001706163,0.0438434,0.001227546,0.002339662,0.7758656,0.004520744,0.0005487169,0.0342095],"study_design_scores_gemma":[0.0005133539,0.002500984,0.6487084,0.00004138652,0.0002624043,0.07863255,0.001973588,0.008307465,0.2453798,0.01163704,0.001979725,0.0000633481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977745,0.0003490585,0.0008321458,0.00005373895,0.000007335292,0.000004381699,0.00003111646,0.00001746075,0.0009301105],"genre_scores_gemma":[0.9996722,0.00006072761,0.00008601527,0.000008227669,0.000003384244,0.000003266583,0.00001844809,0.000003107376,0.0001447211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001753617,"threshold_uncertainty_score":0.005866468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05937715085095763,"score_gpt":0.3302239064588808,"score_spread":0.2708467556079232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}