{"id":"W1995690236","doi":"10.1152/physiolgenomics.00218.2009","title":"Vascular gene expression in mice overexpressing human endothelin-1 targeted to the endothelium","year":2010,"lang":"en","type":"article","venue":"Physiological Genomics","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Gene expression; Gene expression profiling; Endothelin 1; Endothelium; Microarray; Gene; Fold change; Microarray analysis techniques; Internal medicine; Endocrinology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004224784,0.0002653427,0.0004372906,0.00009789176,0.000179905,0.00003203187,0.0003483144,0.0001937664,0.0001924525],"category_scores_gemma":[0.0003126336,0.000158806,0.0002018931,0.0001997419,0.00008872922,0.00005027333,0.0002100832,0.0007362287,0.0002198096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005813979,"about_ca_system_score_gemma":0.00004047179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005688202,"about_ca_topic_score_gemma":0.00001275672,"domain_scores_codex":[0.9982693,0.0001346682,0.0003650125,0.0005008779,0.0002204684,0.0005096592],"domain_scores_gemma":[0.9988431,0.0001994874,0.00008891479,0.0006091053,0.00004687658,0.0002124925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001340336,0.0001842828,0.0006288799,0.00001923448,0.00001791398,0.00002158299,0.0002252133,0.0002415018,0.9972951,0.0000785654,0.0002924238,0.0008612976],"study_design_scores_gemma":[0.001556129,0.0002362135,0.02943837,0.00004568015,0.0000343987,0.00002101569,0.00007799624,0.0002932499,0.9568759,0.0009584704,0.01019275,0.0002698334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973394,0.0002267339,0.0003314061,0.0003105657,0.0002649005,0.000721104,0.00002329156,0.00008359238,0.0006989927],"genre_scores_gemma":[0.9885692,0.00006169178,0.00796287,0.002083583,0.0009641258,0.00008257064,0.00003123095,0.00004014253,0.0002046047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04041917,"threshold_uncertainty_score":0.6475921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0215064774341254,"score_gpt":0.2719207298802301,"score_spread":0.2504142524461047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}