{"id":"W1995707137","doi":"10.4161/chan.25437","title":"Cholesterol sensitivity of KIR2.1 depends on functional inter-links between the N and C termini","year":2013,"lang":"en","type":"article","venue":"Channels","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Sensitivity (control systems); Cholesterol; Chemistry; Biology; Computational biology; Biochemistry; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001369632,0.0002283512,0.0002496373,0.0001291777,0.0001876278,0.0003687557,0.000184619,0.000232427,0.001072754],"category_scores_gemma":[0.0002647336,0.00009102485,0.0001863993,0.0001450513,0.000327162,0.0002275665,0.000296006,0.0003853898,0.0002827645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003286911,"about_ca_system_score_gemma":0.0002205662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006420424,"about_ca_topic_score_gemma":0.0006190963,"domain_scores_codex":[0.9998241,0.0000296019,0.0000222122,0.00003300196,0.00004749668,0.00004356824],"domain_scores_gemma":[0.9998264,0.0000387629,0.00005052011,0.00001967033,0.0000220099,0.00004262598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001051941,0.00001130429,0.0004048535,0.00000937806,0.000002132343,0.00005717871,0.000009840266,0.00003716314,0.9988461,0.00007348764,0.000008962664,0.0004344562],"study_design_scores_gemma":[0.00002674165,0.0001594231,0.02441622,0.000005531053,0.00001328678,0.0009594665,0.00004146913,0.001365039,0.9717997,0.0002101462,0.0009909059,0.00001208311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982257,0.000394516,0.000504662,0.00004835323,0.000006862297,0.000005049249,0.00005911832,0.00001108662,0.0007445122],"genre_scores_gemma":[0.9991032,0.0001460639,0.0003202012,0.00003559348,0.000003551449,0.000006303557,0.00007759428,0.000006912006,0.0003005835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001072754,"threshold_uncertainty_score":0.003588736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01811279914898597,"score_gpt":0.2449000914546706,"score_spread":0.2267872923056846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}