{"id":"W1995731522","doi":"10.3402/jev.v3.24646","title":"Different immunogenicity but similar antitumor efficacy of two DNA vaccines coding for an antigen secreted in different membrane vesicle‐associated forms","year":2014,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National Du Cancer; Institute of Cancer Research; Université Pierre et Marie Curie; Ligue Contre le Cancer","keywords":"DNA vaccination; Antigen; Biology; Immunogenicity; Immune system; Naked DNA; Ovalbumin; Virology; Antibody; Cytotoxic T cell; Plasmid; Molecular biology; Immunology; DNA; Immunization; In vitro; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004683555,0.0005330353,0.0005345917,0.000497631,0.00008578049,0.0004175364,0.0002675001,0.000657508,0.0007989499],"category_scores_gemma":[0.0004798003,0.000158773,0.0004226084,0.0002725729,0.0004799663,0.0003837858,0.0002674599,0.001158413,0.0002070464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002438359,"about_ca_system_score_gemma":0.0002596925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001180024,"about_ca_topic_score_gemma":0.00007252114,"domain_scores_codex":[0.9995959,0.00009492112,0.00003985745,0.00007531944,0.0001001516,0.00009391085],"domain_scores_gemma":[0.9995689,0.0001527112,0.00007144413,0.00006498687,0.00005269206,0.00008925603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007000148,0.0002934613,0.0003502094,0.0001194104,0.00002793355,0.00003658116,0.00003394538,0.0002397671,0.9928517,0.0002973853,0.00003386703,0.005015762],"study_design_scores_gemma":[0.0002102673,0.01042698,0.005825774,0.00001755411,0.0001433171,0.00057149,0.00003327879,0.001020188,0.979427,0.0002483281,0.002063585,0.00001228422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944165,0.001781106,0.002355443,0.00007532134,0.0001026224,0.00005252429,0.0001272746,0.00005106705,0.001038199],"genre_scores_gemma":[0.9969481,0.0004523213,0.001435687,0.00005628288,0.00003054554,0.00005887711,0.0003552096,0.00001466112,0.0006484789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007989499,"threshold_uncertainty_score":0.002672732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01600940046951615,"score_gpt":0.2719762841131772,"score_spread":0.255966883643661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}