{"id":"W1995785316","doi":"10.1016/j.antiviral.2004.05.006","title":"The synergistic effects of betulin with acyclovir against herpes simplex viruses","year":2004,"lang":"en","type":"article","venue":"Antiviral Research","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; St. Paul's Hospital","funders":"","keywords":"Betulin; Herpes simplex virus; Vero cell; EC50; Cytotoxicity; Chemistry; Virology; Pharmacology; Microbiology; In vitro; Virus; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000504501,0.0001275217,0.000142483,0.00004668204,0.0002973608,0.00004693823,0.000325167,0.00009095547,9.297447e-7],"category_scores_gemma":[0.0007153783,0.00007425166,0.00006902352,0.0002097319,0.0006184204,0.000007497012,0.0001640374,0.0001706811,0.00001056315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000182117,"about_ca_system_score_gemma":0.0001435706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002117838,"about_ca_topic_score_gemma":0.0001737986,"domain_scores_codex":[0.9985751,0.0001826829,0.0001391499,0.000297565,0.0003826299,0.0004229],"domain_scores_gemma":[0.9990367,0.0002941881,0.00004879363,0.0004247282,0.0001589364,0.00003662728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003043354,0.00007996199,0.0001724489,0.0000553951,0.00008113995,0.00001394526,0.00002894824,0.000007296723,0.932125,0.0005263746,0.0004825963,0.06612261],"study_design_scores_gemma":[0.0003586336,0.0004934152,0.001077368,0.00004498845,0.000007200047,8.893243e-7,0.0001182873,0.000002798758,0.9769561,0.0003523904,0.02047798,0.0001099869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963186,0.001594224,0.00006711359,0.0004887574,0.0000507331,0.000248053,0.000008578671,0.000007336452,0.001216549],"genre_scores_gemma":[0.9981154,0.0009363071,0.0001094589,0.00006859477,0.0001787545,0.00001866665,0.000009108703,0.00002111735,0.0005426457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06601262,"threshold_uncertainty_score":0.3027895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0216731183844416,"score_gpt":0.3243221376922729,"score_spread":0.3026490193078313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}