{"id":"W1995839839","doi":"10.1002/cbic.200600565","title":"In Vivo Screening Identifies a Highly Folded β‐Hairpin Peptide with a Structured Extension","year":2007,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canada Research Chairs; University of Alberta","keywords":"Haystack; In vivo; Peptide; Computational biology; Chemistry; Förster resonance energy transfer; Extension (predicate logic); Small hairpin RNA; Biophysics; Nanotechnology; Biochemistry; Biology; Materials science; Physics; Computer science; Genetics; Fluorescence; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002581255,0.0002153486,0.0002414214,0.0000743017,0.00005671748,0.00003369269,0.0001898903,0.0001832745,0.00007284539],"category_scores_gemma":[0.0001057198,0.0001812886,0.0001314458,0.0002446483,0.00008442256,0.000007226875,0.0001044764,0.0001079284,0.000003896114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002152932,"about_ca_system_score_gemma":0.00002112726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005886071,"about_ca_topic_score_gemma":0.0002701027,"domain_scores_codex":[0.9986299,0.00001531213,0.0002733102,0.000515885,0.0001965748,0.0003689672],"domain_scores_gemma":[0.9992961,0.00002169043,0.00009791031,0.0003935222,0.0000746363,0.0001161309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001764054,0.00004466908,0.001241366,0.00001714897,0.00005357709,0.0000235617,0.00004139416,0.000005685953,0.9958144,0.00001256906,0.001697987,0.0008712507],"study_design_scores_gemma":[0.0006204003,0.00004456735,0.002769791,0.00005061633,0.00003125531,0.00001784495,0.0001991687,0.00002013795,0.9919241,0.00005365656,0.003999955,0.0002685048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996684,0.0004416252,0.001499505,0.0001396669,0.00003105156,0.0000964315,0.000005541087,0.00001777858,0.001084384],"genre_scores_gemma":[0.9956929,0.000031161,0.002061226,0.0002449056,0.0002076473,0.000008210947,0.00004202669,0.00002856531,0.001683361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003890283,"threshold_uncertainty_score":0.7392733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006895107870365529,"score_gpt":0.2307492674083673,"score_spread":0.2238541595380017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}