{"id":"W1995874313","doi":"10.1039/c2an35839e","title":"Monitoring methotrexate in clinical samples from cancer patients during chemotherapy with a LSPR-based competitive sensor","year":2012,"lang":"en","type":"article","venue":"The Analyst","topic":"Spectroscopy Techniques in Biomedical and Chemical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"","keywords":"Methotrexate; Cancer chemotherapy; Chemotherapy; Cancer; Medicine; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009454105,0.0009205767,0.0008978306,0.0006204495,0.000210648,0.0004750111,0.0007230327,0.001511351,0.0004639662],"category_scores_gemma":[0.001853229,0.000321272,0.0003538184,0.0006598039,0.0002938423,0.000253701,0.00033991,0.0007312639,0.0004990006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00044061,"about_ca_system_score_gemma":0.0003415214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007526195,"about_ca_topic_score_gemma":0.001306142,"domain_scores_codex":[0.997651,0.0006095357,0.0001257645,0.0005290604,0.0009735041,0.0001111372],"domain_scores_gemma":[0.9989997,0.0003451168,0.00025171,0.00006292407,0.00028594,0.0000545904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007208607,0.0001670271,0.0118403,0.0002820259,0.0001174596,0.0002532738,0.0001513892,0.0006067778,0.9641341,0.00009049912,0.0004833677,0.02115288],"study_design_scores_gemma":[0.00005852871,0.002109734,0.01851786,0.00002921588,0.0002302719,0.003838347,0.00008509967,0.0153093,0.956205,0.0000630468,0.003503718,0.00005002108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8654609,0.01967152,0.105146,0.00082036,0.0003141027,0.0006475604,0.001936472,0.002338234,0.003664847],"genre_scores_gemma":[0.8971246,0.002792779,0.09422328,0.0007475577,0.0001837794,0.0005823668,0.001236369,0.00004800606,0.003061272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001511351,"threshold_uncertainty_score":0.004999816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02815611745220856,"score_gpt":0.3809938329566429,"score_spread":0.3528377155044343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}