{"id":"W1995921910","doi":"10.1002/jcp.20508","title":"Proteasome subunit LMP2 is required for matrix metalloproteinase‐2 and ‐9 expression and activities in human invasive extravillous trophoblast cell line","year":2005,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Florida State University","keywords":"Proteasome; Trophoblast; Transfection; Biology; Cell culture; Matrix metalloproteinase; Cell biology; Protein subunit; Proteasome inhibitor; Molecular biology; Biochemistry; Gene; Fetus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002354703,0.0001929507,0.0003542184,0.0001124648,0.0000834159,0.00001804758,0.0001276841,0.0002113024,0.00001684021],"category_scores_gemma":[0.00003725246,0.0001636674,0.0001104111,0.00004059274,0.00009384273,0.0000275444,0.00009601021,0.0001700441,5.810152e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001637331,"about_ca_system_score_gemma":0.00006592135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004768898,"about_ca_topic_score_gemma":0.000005814964,"domain_scores_codex":[0.9989016,0.0001118846,0.0003877049,0.0002571969,0.00009937712,0.0002422308],"domain_scores_gemma":[0.9992743,0.0000214377,0.0003549015,0.0001664959,0.00008386636,0.00009905373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004737854,0.0001289411,0.00001146112,0.00009403486,0.00002660425,0.000009768941,0.0001209101,0.00001596585,0.9986779,0.00002898671,0.0001295493,0.0002820939],"study_design_scores_gemma":[0.001933352,0.002043199,0.00003907729,0.00006451335,0.00002751063,0.00004338863,0.0001354667,0.00003454369,0.9922174,0.001097117,0.00218864,0.0001757574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946833,0.003780268,0.0008921209,0.0001048884,0.00005343533,0.000444096,0.00001483967,0.000002979203,0.00002410744],"genre_scores_gemma":[0.9963698,0.0004051087,0.002113676,0.0001147373,0.0005854268,0.00003761745,0.00001989576,0.00002569333,0.000328031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006460465,"threshold_uncertainty_score":0.6674165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009643356919471902,"score_gpt":0.2447837954059494,"score_spread":0.2351404384864775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}