{"id":"W1995949033","doi":"10.1016/j.bbrc.2014.04.082","title":"MTHFR promotes heterochromatin maintenance","year":2014,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Chinese Academy of Agricultural Sciences; Petroleum Technology Research Centre; National Natural Science Foundation of China","keywords":"Methylenetetrahydrofolate reductase; Cyclin-dependent kinase 1; Phosphorylation; Biology; Heterochromatin; Kinase; Methylation; Biochemistry; Molecular biology; Cell cycle; Cell; DNA; Chromatin; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001098059,0.0001768365,0.0001628943,0.0002149443,0.0002186495,0.0002247264,0.0001421614,0.0002766834,0.002796876],"category_scores_gemma":[0.0001418619,0.0001354247,0.0001746564,0.0001012426,0.0001477304,0.0001632174,0.0002238836,0.0002998272,0.0007868715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003541585,"about_ca_system_score_gemma":0.0001878782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001584795,"about_ca_topic_score_gemma":0.001908628,"domain_scores_codex":[0.9999028,0.00001281164,0.000005051374,0.00003789875,0.00002017224,0.00002129541],"domain_scores_gemma":[0.9999111,0.00001151072,0.00002390384,0.000009918764,0.00001705321,0.00002649445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005621247,0.000008853356,0.00025452,0.00002423749,0.000002882702,0.00002860658,0.0000141687,0.00001586945,0.9979473,0.0001415546,0.00008936587,0.001416384],"study_design_scores_gemma":[0.00002510994,0.00018349,0.0317544,0.0000139491,0.00001755245,0.0003741558,0.00004602149,0.0008211175,0.951755,0.0002632806,0.01473913,0.000006732184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9751533,0.01288069,0.004688573,0.000401564,0.00008008335,0.00002982081,0.0002615505,0.0003002975,0.006204166],"genre_scores_gemma":[0.9925811,0.001438131,0.0009663362,0.00005517353,0.0000173208,0.000008090859,0.0001818858,0.00002144021,0.004730511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002796876,"threshold_uncertainty_score":0.009356499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08771800866814815,"score_gpt":0.4021382312420784,"score_spread":0.3144202225739302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}