{"id":"W1996071843","doi":"10.1385/cbb:33:2:101","title":"Structure and Function of S-Adenosylhomocysteine Hydrolase","year":2000,"lang":"en","type":"review","venue":"Cell Biochemistry and Biophysics","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":166,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Transmethylation; Cofactor; NAD+ kinase; Nicotinamide adenine dinucleotide; Hydrolase; Enzyme; Stereochemistry; Chemistry; Active site; Nicotinamide mononucleotide; Oxidoreductase; Binding site; Biochemistry; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003950623,0.0003005519,0.0009143755,0.00005301451,0.00004518804,0.00001712228,0.00006577977,0.0004404183,0.00007712018],"category_scores_gemma":[0.000006577976,0.0002174874,0.0001582078,0.0002166553,0.000176023,0.00002522395,0.00005907493,0.0003955422,0.000006181112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001865427,"about_ca_system_score_gemma":0.0001389973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003992925,"about_ca_topic_score_gemma":6.084234e-8,"domain_scores_codex":[0.9989719,0.0000185054,0.0002834966,0.00037092,0.0001745813,0.0001806302],"domain_scores_gemma":[0.9993427,0.00003175091,0.000125481,0.0003072722,0.0000429041,0.0001498781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007316828,0.00009750442,0.000003997262,0.07223944,0.0001364623,0.0000316029,0.00001037427,1.961197e-8,0.04241632,0.000002037681,0.0001842466,0.8848048],"study_design_scores_gemma":[0.00103756,0.0006177145,0.000007344902,0.007503396,0.002590145,0.0002320128,0.00001785401,0.00001140357,0.2146032,0.00004353885,0.7728475,0.0004882828],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07277253,0.9259101,4.810337e-7,0.000006474767,0.00002526444,0.000235627,0.0001542911,0.00001269397,0.0008825629],"genre_scores_gemma":[0.02632604,0.9702861,0.00002124779,0.00001132769,0.0002816467,0.000004639318,0.0005382623,0.00002553639,0.002505231],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8843166,"threshold_uncertainty_score":0.8868877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01564038209952318,"score_gpt":0.2759905204847853,"score_spread":0.2603501383852622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}