{"id":"W1996104314","doi":"10.1016/j.pain.2010.10.005","title":"RhoA/Rho kinase pathway contributes to the pathogenesis of thermal hyperalgesia in diabetic mice","year":2010,"lang":"en","type":"article","venue":"Pain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cegep de Sept Iles","funders":"","keywords":"RHOA; Diabetic neuropathy; Hyperalgesia; Medicine; Pharmacology; Streptozotocin; Rho-associated protein kinase; Diabetes mellitus; Internal medicine; Endocrinology; Chemistry; Kinase; Nociception; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002561883,0.0005756269,0.0004987861,0.0007575437,0.0002694753,0.0003478903,0.0002603194,0.0005334195,0.001724187],"category_scores_gemma":[0.0001090908,0.0003362357,0.0008605919,0.0003599699,0.0003118579,0.00034247,0.0002977881,0.001814346,0.0003665849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002835939,"about_ca_system_score_gemma":0.0003149963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000523055,"about_ca_topic_score_gemma":0.0004785814,"domain_scores_codex":[0.9997898,0.00003527086,0.00002609261,0.00004112797,0.00004237188,0.00006527606],"domain_scores_gemma":[0.9998542,0.000005927417,0.00006109235,0.00001173959,0.00001202911,0.00005489836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001577003,0.0003380497,0.001188992,0.000193636,0.00004210329,0.0003358812,0.00004401187,0.0001192373,0.9917605,0.0004113171,0.0001922572,0.003797032],"study_design_scores_gemma":[0.0009474994,0.004729724,0.1192305,0.0002586457,0.0004878928,0.004165915,0.0004012449,0.008113781,0.8503324,0.001610529,0.009647619,0.00007432711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841963,0.006636169,0.005231348,0.000712066,0.0001096875,0.00009628551,0.0006983226,0.0002308931,0.002088926],"genre_scores_gemma":[0.987617,0.005378427,0.002728675,0.0003105963,0.00004885552,0.0002108047,0.0006305545,0.00003096881,0.003044075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001724187,"threshold_uncertainty_score":0.005767941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007442975107022692,"score_gpt":0.2271351417495135,"score_spread":0.2196921666424908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}