{"id":"W1996112172","doi":"10.1074/jbc.m109.012948","title":"Heparan Sulfate Proteoglycans Are Receptors for the Cell-surface Trafficking and Biological Activity of Transglutaminase-2","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Blood properties and coagulation","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of California, San Diego; Trent University; Nottingham Trent University","keywords":"Syndecan 1; Fibronectin; Heparan sulfate; Tissue transglutaminase; Extracellular matrix; Extracellular; Cell biology; Cell adhesion; Biochemistry; Cell; Chemistry; Cell surface receptor; Biology; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000885011,0.0005569734,0.0002196068,0.0002204796,0.0001398127,0.0003518373,0.0001691651,0.0002414056,0.003159707],"category_scores_gemma":[0.000109372,0.0001578927,0.0002503829,0.0001388562,0.0001415313,0.0002086731,0.0002544631,0.000246644,0.001044392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003032826,"about_ca_system_score_gemma":0.0001136591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008349821,"about_ca_topic_score_gemma":0.0008060379,"domain_scores_codex":[0.9998999,0.00002180534,0.000006392718,0.0000188989,0.00002775451,0.00002515929],"domain_scores_gemma":[0.9999427,0.000006233105,0.00001562865,0.00000607942,0.00001355243,0.00001583827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009590337,0.00001283746,0.001001822,0.00006240391,0.00001575274,0.0002857867,0.00003816039,0.00006201609,0.992224,0.0005045085,0.0002778109,0.005418986],"study_design_scores_gemma":[0.00006000195,0.0004665987,0.05093108,0.00004512143,0.00007332477,0.004187819,0.0002416631,0.002790321,0.8817118,0.00103341,0.05841985,0.00003897961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660362,0.01545487,0.009482732,0.0002964955,0.0001125108,0.00009359937,0.0007353968,0.0002695244,0.007518766],"genre_scores_gemma":[0.9765212,0.003457018,0.002521185,0.000153097,0.00004279045,0.00002646193,0.0008867902,0.00002180405,0.01636954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003159707,"threshold_uncertainty_score":0.01057023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04443248410334613,"score_gpt":0.2660311670273718,"score_spread":0.2215986829240257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}