{"id":"W1996129554","doi":"10.1097/00003246-200208000-00003","title":"Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor-α and interleukin-6 messenger RNA*","year":2002,"lang":"en","type":"article","venue":"Critical Care Medicine","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"In situ hybridization; Medicine; Tumor necrosis factor alpha; Ventilation (architecture); Lung; Pathology; Tidal volume; Immunocytochemistry; Cytokine; Mechanical ventilation; Internal medicine; Respiratory system; Biology; Messenger RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000128183,0.0002161781,0.0005262584,0.000186433,0.00007122489,0.000009670302,0.00008415719,0.0001399875,0.002176969],"category_scores_gemma":[0.0007511981,0.0001584536,0.00007723342,0.0001431932,0.0003914283,0.0001385456,0.0000620684,0.0002684526,0.00001860511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003977375,"about_ca_system_score_gemma":0.00002725171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002025176,"about_ca_topic_score_gemma":0.000001439502,"domain_scores_codex":[0.9983844,0.00005824564,0.0004742683,0.0003412237,0.000470262,0.0002716156],"domain_scores_gemma":[0.9988202,0.0002054378,0.00007884343,0.0002869892,0.0002787448,0.0003297379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001908349,0.0001037475,0.003089237,0.0006009904,0.00001055921,0.0002388819,0.00208326,2.990803e-8,0.9672185,0.0001536008,0.0006692031,0.02564112],"study_design_scores_gemma":[0.001552192,0.002057669,0.0147583,0.00175224,0.0002516306,0.0001523748,0.00412912,0.00004953225,0.9698893,0.0003091054,0.004861547,0.0002369262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924176,0.003001097,0.0001488587,0.001085719,0.0005619623,0.0002849466,0.00002411971,0.00005603305,0.002419617],"genre_scores_gemma":[0.9983902,0.00004434554,0.0002649,0.0005870055,0.0003903364,0.00001832931,0.00002482277,0.00003044369,0.0002496185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02540419,"threshold_uncertainty_score":0.9987352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03515588188281864,"score_gpt":0.3094099519891008,"score_spread":0.2742540701062821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}