{"id":"W1996141967","doi":"10.1002/1097-0142(20010801)92:3<595::aid-cncr1359>3.0.co;2-d","title":"Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced nonsmall cell lung carcinoma","year":2001,"lang":"en","type":"article","venue":"Cancer","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Cancer Care Ontario; University of Toronto; Princess Margaret Cancer Centre","funders":"National Cancer Institute; Eli Lilly Canada; Eli Lilly and Company","keywords":"Pemetrexed; Medicine; Antifolate; Performance status; Internal medicine; Phases of clinical research; Gastroenterology; Cisplatin; Neutropenia; Chemotherapy; Surgery; Urology; Oncology; Antimetabolite","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003032854,0.0001728203,0.0003142297,0.0001302287,0.00008475706,0.000005727657,0.00004157982,0.00003755455,0.0001326199],"category_scores_gemma":[0.000009189736,0.0001225201,0.00002597541,0.0003390242,0.00003147686,0.00009514621,0.00001969365,0.00008575738,7.85046e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001229297,"about_ca_system_score_gemma":0.00009468628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001303509,"about_ca_topic_score_gemma":0.001124867,"domain_scores_codex":[0.9990916,0.00001761649,0.0002370581,0.0002858124,0.0001761397,0.0001918288],"domain_scores_gemma":[0.9994233,0.00002705291,0.0001113928,0.0002047471,0.0001420612,0.00009142964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003357086,0.00766968,0.967853,0.00004747038,0.0001454902,0.00003502752,0.005132119,0.0001018529,0.0005716078,6.760089e-7,0.00004109304,0.01504497],"study_design_scores_gemma":[0.09464965,0.01452159,0.8881086,0.0001255916,0.0002403636,0.000001244004,0.0006081306,0.0005386909,0.0006753464,0.000001712862,0.0003683055,0.0001607813],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960708,0.001646296,0.00001035639,0.00009220917,0.00006689296,0.001781609,0.00004778761,0.00001806168,0.000265982],"genre_scores_gemma":[0.9987381,0.0003375507,0.0001450596,0.00008114507,0.00002117391,0.0001969907,0.00006016135,0.00002734512,0.000392462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09129257,"threshold_uncertainty_score":0.4996224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01090290980460885,"score_gpt":0.3144783918800072,"score_spread":0.3035754820753984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}