{"id":"W1996145257","doi":"10.1371/journal.ppat.0030015","title":"Newly Synthesized APOBEC3G Is Incorporated into HIV Virions, Inhibited by HIV RNA, and Subsequently Activated by RNase H","year":2007,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Public Health Service; Gladstone Institutes; McGill University; University of California, San Francisco; Center for AIDS Research, University of Washington","keywords":"Cytidine deaminase; RNA; APOBEC3G; RNase P; Biology; Non-coding RNA; Reverse transcriptase; RNase H; Transcription (linguistics); Enzyme; Molecular biology; Cell biology; Biochemistry; Virology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003829191,0.0003889608,0.0004692081,0.0002858386,0.0003988496,0.00004585197,0.0002130588,0.0004156489,0.000833355],"category_scores_gemma":[0.0002409865,0.0003349699,0.00009702501,0.0004233118,0.0003390846,0.0001565314,0.0001299594,0.0004475666,0.002245557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001751932,"about_ca_system_score_gemma":0.0001140555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002174727,"about_ca_topic_score_gemma":0.00005242011,"domain_scores_codex":[0.9976209,0.0003402297,0.0004612117,0.0006248687,0.0001268386,0.0008259463],"domain_scores_gemma":[0.998694,0.0003243242,0.0001787049,0.0004187084,0.0001615526,0.0002226873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006750596,0.0007382937,0.006024117,0.00002125204,0.000506924,0.0001441915,0.00046601,1.331821e-7,0.9343163,0.00001740649,0.05306734,0.004022949],"study_design_scores_gemma":[0.003466408,0.0002457351,0.0006428178,0.00005105865,0.0001083466,0.00003806191,0.0002080583,0.000007207778,0.9629306,0.00006744471,0.03189041,0.0003438114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909916,0.003842682,0.0002743051,0.001116816,0.00006721121,0.0006361622,0.002303356,0.0001937757,0.0005740968],"genre_scores_gemma":[0.9893572,0.0004420634,0.0003640126,0.000391002,0.00002014443,0.00006232622,0.003682726,0.00005733228,0.005623184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02861431,"threshold_uncertainty_score":0.9999102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01248341547346837,"score_gpt":0.2377571703431599,"score_spread":0.2252737548696915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}