{"id":"W1996228069","doi":"10.1081/scc-120017198","title":"Syntheses of 4-(3,5-Bisphenylmethylene-4-oxo-piperidin-1-yl)-4-oxo-but-2<b><i>Z</i></b>-enoic Acid Arylamides as Candidate Cytotoxic Agents","year":2003,"lang":"en","type":"article","venue":"Synthetic Communications","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Purdue University","keywords":"Chemistry; Cytotoxic T cell; Combinatorial chemistry; Stereochemistry; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009433019,0.0004622674,0.0007188375,0.0001168821,0.0007474911,0.00007099767,0.00195442,0.0003043047,0.005175505],"category_scores_gemma":[0.004521845,0.0003887423,0.000394553,0.0003498736,0.0009191484,0.0001548832,0.00050632,0.0006756529,0.0002917551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001348224,"about_ca_system_score_gemma":0.0001653427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003745052,"about_ca_topic_score_gemma":0.0001242387,"domain_scores_codex":[0.9968443,0.0007713369,0.0007953902,0.0005873772,0.0004029678,0.00059866],"domain_scores_gemma":[0.9922675,0.003100492,0.000465125,0.003760962,0.000168279,0.0002376738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005448806,0.001226235,0.002776357,0.0001070788,0.0002142301,0.000004941185,0.0003885176,0.00000520556,0.9740752,0.004398589,0.0001364158,0.01661274],"study_design_scores_gemma":[0.0002524164,0.00006740809,0.0004488735,0.0002859538,0.0001445426,0.0000493202,0.001489349,0.00006486771,0.9531878,0.00303751,0.04047167,0.0005003039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8558694,0.001701318,0.00007833347,0.0006777564,0.00007129798,0.000237042,0.0001969837,0.0001856648,0.1409822],"genre_scores_gemma":[0.9933822,0.001969798,0.002719854,0.0001078283,0.00003121824,0.000213054,0.00003432342,0.00005628849,0.001485483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1394967,"threshold_uncertainty_score":0.9998565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04706284050530848,"score_gpt":0.2866911304344403,"score_spread":0.2396282899291318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}