{"id":"W1996228069","doi":"10.1081/scc-120017198","title":"Syntheses of 4-(3,5-Bisphenylmethylene-4-oxo-piperidin-1-yl)-4-oxo-but-2<b><i>Z</i></b>-enoic Acid Arylamides as Candidate Cytotoxic Agents","year":2003,"lang":"en","type":"article","venue":"Synthetic Communications","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Purdue University","keywords":"Chemistry; Cytotoxic T cell; Combinatorial chemistry; Stereochemistry; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000267015,0.0005370821,0.0003292274,0.0003038858,0.0001896226,0.0002171532,0.0003541493,0.0002209815,0.002799243],"category_scores_gemma":[0.0002115004,0.0001984387,0.0001615369,0.0002623193,0.0001470144,0.0002742804,0.0002008147,0.0003211042,0.001185545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001843873,"about_ca_system_score_gemma":0.0005484079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002547816,"about_ca_topic_score_gemma":0.0007764935,"domain_scores_codex":[0.9998848,0.00002430554,0.00001567877,0.0000200822,0.00002545994,0.00002952892],"domain_scores_gemma":[0.9998914,0.00001359199,0.00002936567,0.00001296289,0.00002005527,0.0000327356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001981835,0.0001134264,0.0001726112,0.0003564304,0.00001275944,0.0005216401,0.00007989809,0.0009411698,0.9808366,0.001569456,0.0002615901,0.0149362],"study_design_scores_gemma":[0.0001048903,0.001075328,0.0007046781,0.00002741322,0.00003378576,0.0003742684,0.00003133971,0.0006008663,0.9796507,0.0001457693,0.01723588,0.00001505179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8927351,0.009770812,0.06339891,0.0002696427,0.0003334176,0.0009726554,0.001612828,0.0005066919,0.03040001],"genre_scores_gemma":[0.936039,0.008841618,0.03895469,0.00008630112,0.00006501652,0.000508772,0.001076613,0.00006636699,0.01436164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002799243,"threshold_uncertainty_score":0.009364426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04706284050530848,"score_gpt":0.2866911304344403,"score_spread":0.2396282899291318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}