{"id":"W1996238004","doi":"10.1186/2041-9414-1-7","title":"UHRF1 is a genome caretaker that facilitates the DNA damage response to γ-irradiation","year":2010,"lang":"en","type":"article","venue":"Genome Integrity","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Defence Science and Technology Group; National Medical Research Council; Medical Research Council; Cancer Research Society","keywords":"Chromatin; DNA damage; Biology; Histone; DNA repair; Cell biology; Epigenetics; DNA; DNA replication; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001264483,0.0005107672,0.0002594693,0.0001709417,0.0002401485,0.0002448733,0.000289573,0.0004281295,0.001187598],"category_scores_gemma":[0.0001465117,0.0001142814,0.000218425,0.00008659324,0.0002742117,0.0001560916,0.0002286324,0.0003117729,0.0005211895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003228613,"about_ca_system_score_gemma":0.0001074512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003718247,"about_ca_topic_score_gemma":0.0003463234,"domain_scores_codex":[0.9999276,0.000007369498,0.000004460645,0.00002412207,0.00001864831,0.00001788572],"domain_scores_gemma":[0.9998914,0.0000130179,0.00004438552,0.00001227826,0.00001128149,0.00002765483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008096472,0.000005827014,0.0003721106,0.00002817726,0.000004867975,0.00006211345,0.000004754161,0.00002699726,0.9981425,0.00005641785,0.00005397442,0.001161306],"study_design_scores_gemma":[0.00001312243,0.0001436896,0.01275789,0.000008536287,0.00002450503,0.0008077021,0.00001594402,0.0003352852,0.980724,0.0000601666,0.005103881,0.000005230334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788795,0.008706832,0.008878202,0.0003202088,0.00005837835,0.0000329418,0.0005482259,0.00025553,0.002320233],"genre_scores_gemma":[0.9923891,0.001219615,0.002923027,0.00005678488,0.00001936284,0.00001409844,0.0007583845,0.0000243518,0.002595194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001187598,"threshold_uncertainty_score":0.003972888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01617506298477833,"score_gpt":0.2526693280316194,"score_spread":0.2364942650468411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}