{"id":"W1996262959","doi":"10.1016/j.apradiso.2014.02.017","title":"Automated radiosynthesis of N-succinimidyl 3-(di-tert-butyl[18F]fluorosilyl)benzoate ([18F]SiFB) for peptides and proteins radiolabeling for positron emission tomography","year":2014,"lang":"en","type":"article","venue":"Applied Radiation and Isotopes","topic":"Medical Imaging Techniques and Applications","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"","keywords":"Radiosynthesis; Chemistry; Yield (engineering); Oxalic acid; Positron emission tomography; Radiochemistry; Specific activity; Peptide; Column chromatography; Combinatorial chemistry; Nuclear chemistry; Chromatography; Organic chemistry; Nuclear medicine; Biochemistry; Materials science; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005685792,0.0005550975,0.0004442114,0.0005840161,0.0002194567,0.0004799888,0.000477801,0.0004430062,0.001501097],"category_scores_gemma":[0.0005720191,0.0003741279,0.000233245,0.0003004069,0.0002359798,0.0003450826,0.0002899474,0.0003341891,0.0008658477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004697747,"about_ca_system_score_gemma":0.0006027021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001924176,"about_ca_topic_score_gemma":0.003713643,"domain_scores_codex":[0.9997608,0.00003719629,0.000009061967,0.00008433245,0.00007417915,0.00003451313],"domain_scores_gemma":[0.9997419,0.0000763369,0.00005790167,0.00004408726,0.00005804144,0.00002169684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001651253,0.00001095429,0.0002310814,0.00004985324,0.00001182356,0.00002875699,0.00001986322,0.000575966,0.9880937,0.0001126293,0.00008363095,0.01061675],"study_design_scores_gemma":[0.00002145621,0.0001596677,0.001431246,0.000006458746,0.00003654024,0.0001678824,0.00001248211,0.01007971,0.9853643,0.00004955204,0.002659837,0.00001092666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.6890447,0.004121652,0.2996708,0.0001317272,0.000102326,0.0002337342,0.0006038746,0.001969417,0.004121766],"genre_scores_gemma":[0.7770819,0.001510863,0.2124724,0.00007574608,0.00003028426,0.000168333,0.00123414,0.0005473625,0.006878939],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001924176,"threshold_uncertainty_score":0.005021632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01000830060690017,"score_gpt":0.269227502922596,"score_spread":0.2592192023156958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}