{"id":"W1996344237","doi":"10.1016/j.bbrc.2005.07.166","title":"LTB4 stimulates growth of human pancreatic cancer cells via MAPK and PI-3 kinase pathways","year":2005,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; Public Health Agency of Canada; Lustgarten Foundation","keywords":"Wortmannin; MAPK/ERK pathway; Kinase; Protein kinase B; Cancer research; Pancreatic cancer; p38 mitogen-activated protein kinases; Cell growth; Cell biology; MEK inhibitor; Chemistry; Phosphorylation; Biology; Internal medicine; Cancer; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002336399,0.0006676093,0.0003650786,0.0006315871,0.0003452553,0.0004211804,0.0002113974,0.000294619,0.003335051],"category_scores_gemma":[0.0002259836,0.0002477785,0.0007062831,0.0005064114,0.0002635962,0.0002424935,0.0004189773,0.0008857728,0.001001346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008000905,"about_ca_system_score_gemma":0.0006264103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00436579,"about_ca_topic_score_gemma":0.003114691,"domain_scores_codex":[0.999777,0.00006141521,0.00001569671,0.00001534859,0.00004449232,0.00008603734],"domain_scores_gemma":[0.9998952,0.00003252431,0.0000119434,0.00001638469,0.00001497455,0.00002893081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003559512,0.0004283509,0.0008136501,0.0001195558,0.00002672041,0.0002374223,0.00006379838,0.0002877151,0.9894944,0.0001957594,0.0003918167,0.00438138],"study_design_scores_gemma":[0.0002569455,0.001370178,0.01202829,0.00001462577,0.00004528288,0.0002573028,0.0001095915,0.001300153,0.9810652,0.0001313404,0.003410933,0.00001017637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907513,0.002825892,0.0008776932,0.0004184266,0.00007404541,0.00004778247,0.000830245,0.0001277074,0.004046952],"genre_scores_gemma":[0.9906561,0.00204321,0.0007792446,0.0001339522,0.00003546571,0.0001011618,0.001981486,0.00002678004,0.004242658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00436579,"threshold_uncertainty_score":0.01115686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06258570404280024,"score_gpt":0.3625062298065578,"score_spread":0.2999205257637576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}