{"id":"W1996346417","doi":"10.1038/leu.2014.183","title":"Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1","year":2014,"lang":"en","type":"article","venue":"Leukemia","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute","keywords":"Survivin; Haematopoiesis; Stem cell; Biology; Cancer research; Gene; Hematology; Hematopoietic stem cell; Cell biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001048082,0.0001387839,0.0001473735,0.00002332343,0.00007598459,0.0000180286,0.00005871959,0.0001184258,0.000008887951],"category_scores_gemma":[0.000003425693,0.0001099656,0.00004380556,0.00006371005,0.00005904453,0.000007445373,0.00005183779,0.00003648984,0.000002321201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001689548,"about_ca_system_score_gemma":0.00003741481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003037843,"about_ca_topic_score_gemma":0.00002226672,"domain_scores_codex":[0.9992339,0.00005237177,0.0001743011,0.0002779336,0.000126602,0.0001348613],"domain_scores_gemma":[0.9995065,0.000008071273,0.00009554913,0.0002629723,0.00008414712,0.00004276987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003864752,0.00001978019,0.0009440562,0.00006723325,0.00003984604,4.608945e-7,0.00007657544,0.007105216,0.9875455,0.001019095,0.00007056117,0.003072958],"study_design_scores_gemma":[0.0003981463,0.0002975655,0.0009024337,0.00002864253,0.00004505254,0.00001189182,0.00006278857,0.003875636,0.9917372,0.0003943322,0.002089065,0.0001571846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9630458,0.000964925,0.03545858,0.00003611616,0.00008376063,0.0002036595,0.000005205735,0.00001273681,0.0001892489],"genre_scores_gemma":[0.9976169,0.0002137323,0.001119165,0.00003401937,0.00006184379,0.00001609221,0.00005673657,0.00002022493,0.0008612733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03457114,"threshold_uncertainty_score":0.4484268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006505756812290964,"score_gpt":0.1957064426378567,"score_spread":0.1892006858255657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}