{"id":"W1996346417","doi":"10.1038/leu.2014.183","title":"Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1","year":2014,"lang":"en","type":"article","venue":"Leukemia","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute","keywords":"Survivin; Haematopoiesis; Stem cell; Biology; Cancer research; Gene; Hematology; Hematopoietic stem cell; Cell biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001970132,0.0003001083,0.000203656,0.0004575756,0.0001785384,0.0006993165,0.0002464703,0.0001745044,0.001093741],"category_scores_gemma":[0.0001729025,0.0001451029,0.0001790747,0.0002542551,0.000304507,0.0003207649,0.0003226149,0.0005634782,0.0003032265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005497542,"about_ca_system_score_gemma":0.0001580905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004033256,"about_ca_topic_score_gemma":0.0005713963,"domain_scores_codex":[0.9997626,0.00003964984,0.00002042194,0.00005335026,0.0000451641,0.00007882304],"domain_scores_gemma":[0.9998792,0.00001488985,0.00004581724,0.00001031583,0.0000192956,0.00003042551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002516404,0.00001817248,0.002018726,0.00002501226,0.0000100097,0.0001089185,0.00003085304,0.00009798338,0.9934756,0.0008965204,0.00008795143,0.002978426],"study_design_scores_gemma":[0.00003016051,0.0002459265,0.03768099,0.00001226834,0.00005790118,0.0006831535,0.0001684443,0.001480825,0.9537612,0.0003669928,0.005504007,0.000008266264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872089,0.005700809,0.002995151,0.0001424698,0.00003761113,0.00001007584,0.0003185026,0.00006976605,0.003516652],"genre_scores_gemma":[0.9960252,0.0009639776,0.00040414,0.00005122195,0.000008754982,0.000007176271,0.0004089326,0.00001598988,0.002114543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001093741,"threshold_uncertainty_score":0.003988743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006505756812290964,"score_gpt":0.1957064426378567,"score_spread":0.1892006858255657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}