{"id":"W1996390383","doi":"10.1016/j.ymthe.2004.01.012","title":"Use of adenovirus protein IX (pIX) to display large polypeptides on the virion—generation of fluorescent virus through the incorporation of pIX-GFP","year":2004,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Green fluorescent protein; Capsid; Fusion protein; Virus; Biology; Fluorescence microscope; Molecular biology; Cell biology; Adenoviridae; Virology; Fluorescence; Gene; Biochemistry; Genetic enhancement; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002277901,0.0003654818,0.0001971747,0.000203108,0.0002095767,0.0004772609,0.0002742245,0.0003623504,0.0005550727],"category_scores_gemma":[0.0001294712,0.000236793,0.0002703675,0.000108343,0.0003247385,0.0003702877,0.000345255,0.000682026,0.0002557559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002917754,"about_ca_system_score_gemma":0.0001894362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002986891,"about_ca_topic_score_gemma":0.0002865433,"domain_scores_codex":[0.9999082,0.00001489415,0.000007780659,0.00002689017,0.00002299005,0.00001929014],"domain_scores_gemma":[0.999915,0.00002716048,0.00001963183,0.00001287658,0.000005754501,0.00001951476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002397058,0.000006755031,0.00005095861,0.00001474921,0.000002827233,0.00002702706,0.0000109549,0.00004783536,0.9984248,0.0004760858,0.00002149877,0.0008925702],"study_design_scores_gemma":[0.000003356662,0.00004018508,0.0001527196,0.000001100644,0.000004672555,0.000151294,0.000004074231,0.0003036372,0.9980195,0.00004205416,0.001275578,0.000001967488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.924877,0.001551993,0.06955929,0.0001979673,0.00007710983,0.00008634046,0.0001750337,0.0002697325,0.003205516],"genre_scores_gemma":[0.95358,0.001076094,0.04074801,0.00004927848,0.00001150587,0.00004202962,0.0003210786,0.00007159031,0.004100526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005550727,"threshold_uncertainty_score":0.002117038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04969659486654338,"score_gpt":0.3036460274424398,"score_spread":0.2539494325758964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}