{"id":"W1996393115","doi":"10.1016/j.jmb.2011.04.076","title":"Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis","year":2011,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Basic Energy Sciences; Biological and Environmental Research; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Michigan Technology Tri-Corridor; Office of Science; National Institutes of Health; Michigan Economic Development Corporation; U.S. Department of Health and Human Services; U.S. Department of Energy","keywords":"Bacillus anthracis; Bacillus subtilis; Antibiotics; Aminoglycoside; Acetyltransferase; Antimicrobial; Microbiology; Cofactor; Biology; Bacteria; Antibiotic resistance; Chemistry; Biochemistry; Enzyme; Genetics; Acetylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002018588,0.0001227676,0.0004845832,0.000272371,0.00003084323,0.000007363351,0.0002044113,0.0001116612,0.0007648404],"category_scores_gemma":[0.00008095476,0.0000881634,0.0002704505,0.000301045,0.0001761134,0.00008923787,0.00002341396,0.0001236697,0.000003368953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002108387,"about_ca_system_score_gemma":0.00004127501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000248464,"about_ca_topic_score_gemma":0.00003381785,"domain_scores_codex":[0.9988471,0.0001997384,0.000500968,0.0001595085,0.0001363615,0.0001563434],"domain_scores_gemma":[0.9990744,0.00005959843,0.0004161874,0.0001590226,0.0002197839,0.0000710142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002593693,0.00001556665,0.002450012,0.000002811536,0.0005476165,0.00005881489,0.001059351,0.0001374065,0.9940236,0.0003418897,0.000007080856,0.00109651],"study_design_scores_gemma":[0.0004248316,0.0005503517,0.01711783,0.000005441173,0.0008606846,0.00003640943,0.0001801898,0.0000774681,0.9771387,0.003485198,0.00002422279,0.00009866332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9542459,0.0004185911,0.04453515,0.00002743142,0.0004181189,0.00003844087,0.0001314767,0.000005326463,0.0001795903],"genre_scores_gemma":[0.9908027,0.00002203475,0.008998896,0.00009708478,0.0000488317,6.466377e-7,0.00002025506,0.000006462642,0.000003088193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03655683,"threshold_uncertainty_score":0.8374466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0197019973034884,"score_gpt":0.2692766686700961,"score_spread":0.2495746713666077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}