{"id":"W1996422185","doi":"10.3390/biom3030578","title":"Decarboxylation of Pyruvate to Acetaldehyde for Ethanol Production by Hyperthermophiles","year":2013,"lang":"en","type":"article","venue":"Biomolecules","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Genome Prairie; Genome Canada","keywords":"Hyperthermophile; Pyrococcus furiosus; Biochemistry; Chemistry; Pyruvate decarboxylation; Acetaldehyde; Pyruvate dehydrogenase complex; Pyruvate decarboxylase; Enzyme; Alcohol dehydrogenase; Archaea; Ethanol; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000841088,0.0001177898,0.0001171848,0.00004054309,0.00004510493,0.00001225922,0.0001406057,0.00009867564,0.000007358476],"category_scores_gemma":[0.0003471924,0.0000989716,0.00006793963,0.0001068483,0.0001383254,0.000003916873,0.0001016651,0.00002893922,0.00001238578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008865533,"about_ca_system_score_gemma":0.00001783055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003750959,"about_ca_topic_score_gemma":0.000005161815,"domain_scores_codex":[0.9991779,0.00002440036,0.0001586201,0.0003032627,0.000124927,0.0002108944],"domain_scores_gemma":[0.9994173,0.00001079948,0.00005135813,0.0002173977,0.0002324945,0.0000706686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005474812,0.00004896596,0.0001131505,0.00003380044,0.00004435365,4.793503e-8,0.00002175694,0.000002022829,0.9747068,0.00001712918,0.01856021,0.006397045],"study_design_scores_gemma":[0.0001717667,0.0002857965,0.0005680182,0.00001205086,0.000007203952,7.932011e-7,0.00003463143,0.00001282184,0.9918952,0.0001493939,0.006740116,0.0001221943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925715,0.001099389,0.002405554,0.002837968,0.00006958724,0.0007676443,0.00004241877,0.00001464837,0.0001912706],"genre_scores_gemma":[0.9963418,0.0001096299,0.002529617,0.0001219762,0.0001226504,0.0002836625,0.0001106087,0.00001992675,0.0003601665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01718844,"threshold_uncertainty_score":0.4035945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009880874435885654,"score_gpt":0.265224513783857,"score_spread":0.2553436393479714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}