{"id":"W1996422185","doi":"10.3390/biom3030578","title":"Decarboxylation of Pyruvate to Acetaldehyde for Ethanol Production by Hyperthermophiles","year":2013,"lang":"en","type":"article","venue":"Biomolecules","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Genome Prairie; Genome Canada","keywords":"Hyperthermophile; Pyrococcus furiosus; Biochemistry; Chemistry; Pyruvate decarboxylation; Acetaldehyde; Pyruvate dehydrogenase complex; Pyruvate decarboxylase; Enzyme; Alcohol dehydrogenase; Archaea; Ethanol; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001226239,0.0005532472,0.0003660174,0.0003328917,0.0001562201,0.0004844377,0.0001154489,0.0002647278,0.0004926944],"category_scores_gemma":[0.0002892108,0.0001837283,0.0003295226,0.0004032191,0.0001288566,0.0003901913,0.0005051112,0.0003699397,0.0005263233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001864939,"about_ca_system_score_gemma":0.0001956212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007196657,"about_ca_topic_score_gemma":0.0005612457,"domain_scores_codex":[0.999826,0.00003013231,0.00001727523,0.00004786998,0.00004412551,0.00003458095],"domain_scores_gemma":[0.9998984,0.0000117955,0.00001954142,0.00001681334,0.00003094953,0.00002234801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000988884,0.00001613579,0.00223854,0.0001422151,0.0000151404,0.0001053246,0.00005465101,0.00005427853,0.9920694,0.00006636849,0.00009100266,0.005048154],"study_design_scores_gemma":[0.00002342948,0.0003015211,0.09005891,0.00007376821,0.0000998937,0.0009214403,0.0003888425,0.001573987,0.8878615,0.0003217138,0.01834342,0.00003163311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873126,0.004240419,0.004362702,0.0001716275,0.00007490468,0.0000516182,0.001931642,0.0001383756,0.001716079],"genre_scores_gemma":[0.9881752,0.001802586,0.003547896,0.0001103312,0.00002443293,0.00002896871,0.004047941,0.00004114701,0.002221614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007196657,"threshold_uncertainty_score":0.001648247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009880874435885654,"score_gpt":0.265224513783857,"score_spread":0.2553436393479714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}