{"id":"W1996458818","doi":"10.1016/j.mce.2012.06.020","title":"Role of AMPK in pancreatic beta cell function","year":2012,"lang":"en","type":"review","venue":"Molecular and Cellular Endocrinology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"","keywords":"AMPK; Metformin; Beta cell; Protein kinase A; Secretion; Insulin; Diabetes mellitus; Endocrinology; AMP-activated protein kinase; Alpha cell; Internal medicine; Type 2 diabetes; Medicine; Kinase; Chemistry; Biology; Cell biology; Islet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001005196,0.0003497397,0.001803727,0.0003986396,0.00002082296,0.000005574381,0.00007594682,0.000300478,0.0002112632],"category_scores_gemma":[0.00002349691,0.0002943665,0.0003226779,0.0002367277,0.0001470102,0.00002619845,0.00007267878,0.0003675421,0.00007336297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004157234,"about_ca_system_score_gemma":0.00009758733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006780543,"about_ca_topic_score_gemma":0.000001576922,"domain_scores_codex":[0.9982615,0.000199273,0.000566547,0.0003647696,0.0001475211,0.0004604554],"domain_scores_gemma":[0.9991128,0.00008176509,0.0002109147,0.0004191225,0.00003420483,0.0001412304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008615667,0.0006015539,0.002379617,0.02913745,0.000636018,0.0002513514,0.00008025201,4.999703e-7,0.02013008,0.004643859,0.00004477705,0.9420084],"study_design_scores_gemma":[0.001209846,0.0003847069,0.000131443,0.001636757,0.005384347,0.0001965654,0.00009543089,0.000005596575,0.009964423,0.0001549218,0.9804962,0.000339753],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008188798,0.9810834,0.0001182675,0.00001123537,0.0001370039,0.0005377774,0.000007297887,0.00002845117,0.009887802],"genre_scores_gemma":[0.04182744,0.9570074,0.0001165913,0.00006226127,0.00006827816,0.0000889009,0.0002105425,0.00005112871,0.0005674796],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9804514,"threshold_uncertainty_score":0.9999508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01879709556446825,"score_gpt":0.2548034028679612,"score_spread":0.236006307303493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}