{"id":"W1996462110","doi":"10.1073/pnas.1215432110","title":"KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization","year":2013,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":263,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; University of Melbourne; School of Medicine, New York University; York University","keywords":"Gene knockdown; Catabolism; Transfection; Glycosaminoglycan; Cell biology; CD44; Receptor; Synovial membrane; Chemistry; Molecular biology; Biochemistry; Cell; Inflammation; Biology; Gene; Immunology; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004930883,0.0001146026,0.0001529835,0.0002202602,0.00009683806,0.00002232803,0.0006302349,0.0001312018,0.00002377709],"category_scores_gemma":[0.000305349,0.00008495063,0.00006797177,0.0008824948,0.0004564323,0.00005281769,0.0001912329,0.0001149693,0.000001013919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001670961,"about_ca_system_score_gemma":0.0001658016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001545404,"about_ca_topic_score_gemma":0.000001417079,"domain_scores_codex":[0.9982933,0.00001359346,0.0003895742,0.0003150443,0.0007753627,0.0002131396],"domain_scores_gemma":[0.9993238,0.00001305486,0.0003429412,0.00002022693,0.0002437963,0.00005610609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003707572,0.00004004592,0.009833838,0.00005906562,0.00001340563,3.31034e-9,0.00005330722,0.0000269859,0.9856094,0.001288841,0.00009930009,0.00293876],"study_design_scores_gemma":[0.0003466921,0.0002710065,0.02542194,0.00007885882,0.000004806761,0.000001723494,0.00008241973,0.000428793,0.9702526,0.002839629,0.0001793977,0.00009216592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997682,0.0002236551,0.00002618216,0.0009192707,0.00001128079,0.0004985155,0.00001120963,0.000003237228,0.000624607],"genre_scores_gemma":[0.9981741,0.00001779755,0.001126719,0.0001011922,0.00006003934,0.00005467709,0.000001615937,0.000007319815,0.0004564871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0155881,"threshold_uncertainty_score":0.3464186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02894187309921423,"score_gpt":0.2830965371433443,"score_spread":0.25415466404413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}