{"id":"W1996468220","doi":"10.1016/j.cell.2009.02.025","title":"Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":330,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; Ubiquitin; Wnt signaling pathway; Cell biology; Convergent extension; Ubiquitin-Protein Ligases; Neural tube; Deubiquitinating enzyme; Morphogenesis; Dishevelled; Cell polarity; Signal transduction; Cell; Ubiquitin ligase; Frizzled; Genetics; Gene; Embryogenesis; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002897526,0.0003745081,0.00025909,0.0003953848,0.0003205726,0.0006341644,0.0002121037,0.0002748019,0.0008872062],"category_scores_gemma":[0.0002389795,0.0001592881,0.0002295697,0.0001680248,0.0002975304,0.0003692436,0.0003803411,0.0002939235,0.0005493802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008184278,"about_ca_system_score_gemma":0.0002099616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008987606,"about_ca_topic_score_gemma":0.00191943,"domain_scores_codex":[0.9997891,0.00003862636,0.000009311217,0.00003046643,0.00004632269,0.00008615613],"domain_scores_gemma":[0.9998785,0.00001317557,0.00003691898,0.0000147211,0.00002639402,0.00003032526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003387491,0.00001309979,0.001098437,0.00004574735,0.0000137331,0.0001784996,0.00002656511,0.0002282591,0.9882514,0.002266835,0.0002770395,0.007261625],"study_design_scores_gemma":[0.00002174837,0.00008264373,0.009736555,0.000005514763,0.00001379008,0.000422658,0.00008618925,0.002701994,0.9793628,0.0005633457,0.006991917,0.00001084513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833236,0.006880519,0.004440968,0.000370338,0.0000378865,0.0000133871,0.0001845557,0.0001507226,0.00459805],"genre_scores_gemma":[0.9947214,0.00109694,0.001361311,0.00004530259,0.00001074062,0.000007258055,0.0001585177,0.00001462731,0.002583825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008987606,"threshold_uncertainty_score":0.005938172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004390668221088379,"score_gpt":0.2074421868849088,"score_spread":0.2030515186638204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}