{"id":"W1996468220","doi":"10.1016/j.cell.2009.02.025","title":"Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":330,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; Ubiquitin; Wnt signaling pathway; Cell biology; Convergent extension; Ubiquitin-Protein Ligases; Neural tube; Deubiquitinating enzyme; Morphogenesis; Dishevelled; Cell polarity; Signal transduction; Cell; Ubiquitin ligase; Frizzled; Genetics; Gene; Embryogenesis; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008150897,0.00008285193,0.00008170686,0.00001913203,0.00004001914,0.000003828843,0.00007550548,0.000151693,0.00002066337],"category_scores_gemma":[0.000006439084,0.00008211946,0.00003919235,0.0000416988,0.00003546644,0.000002603317,0.00001404533,0.00003452941,0.00001092746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006257114,"about_ca_system_score_gemma":0.00002476562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005608354,"about_ca_topic_score_gemma":0.000002303646,"domain_scores_codex":[0.9994891,0.00002916088,0.0001417913,0.0001721314,0.00005287923,0.0001149217],"domain_scores_gemma":[0.9997171,0.000004587379,0.00007699784,0.0001382774,0.00002869136,0.0000343365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004029188,0.0000725413,0.001778032,0.000009026733,0.000003570797,2.251444e-7,0.00001667029,0.000004864136,0.9910107,0.00001768732,0.005832925,0.001213438],"study_design_scores_gemma":[0.0002401603,0.000187273,0.03735575,0.000003195329,0.000005845651,0.000001735402,0.0000136047,0.000005014039,0.9488201,0.0002443916,0.0130306,0.00009232386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913365,0.0009513846,0.0004260784,0.0001103832,0.00005425081,0.0000813377,0.00002723145,0.000007722399,0.007005057],"genre_scores_gemma":[0.9952487,0.00006693324,0.0007714991,0.0001975578,0.00004691608,0.000001212854,0.0009050392,0.00000451377,0.002757568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04219062,"threshold_uncertainty_score":0.3348734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004390668221088379,"score_gpt":0.2074421868849088,"score_spread":0.2030515186638204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}