{"id":"W1996533937","doi":"10.1038/nature10579","title":"Control of Drosophila endocycles by E2F and CRL4CDT2","year":2011,"lang":"en","type":"article","venue":"Nature","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":163,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"Biology; Cell division control protein 4; Cell biology; PLK1; Cyclin-dependent kinase 1; Cell cycle; Mitosis; Ubiquitin ligase; E2F1; Cyclin A; Cyclin-dependent kinase; E2F; DNA replication; DNA re-replication; Genetics; Ubiquitin; DNA; Control of chromosome duplication; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002064248,0.0004155328,0.000249843,0.0004632818,0.0004295163,0.0009829079,0.0005176069,0.0003745749,0.002145873],"category_scores_gemma":[0.0002963352,0.0003036353,0.0001933601,0.0001769973,0.0004417594,0.0004016083,0.0005024677,0.0005251913,0.0007411088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001588472,"about_ca_system_score_gemma":0.0003370492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002292352,"about_ca_topic_score_gemma":0.005985383,"domain_scores_codex":[0.9998021,0.00001728482,0.00001544692,0.00006235299,0.00005062909,0.00005214331],"domain_scores_gemma":[0.999761,0.00003359771,0.00008453328,0.00002820485,0.00003736724,0.00005521162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002100458,0.00001896252,0.0005370546,0.00001896866,0.00000463231,0.0000708319,0.00001720454,0.0002160439,0.9945926,0.0009207336,0.0002269292,0.003165878],"study_design_scores_gemma":[0.00004494088,0.00002252475,0.006548526,0.000003980176,0.000004875427,0.0001000629,0.00003707851,0.004707554,0.984558,0.0001494101,0.003814108,0.000008890969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863805,0.001737788,0.004735919,0.0004272938,0.00008123444,0.00002182669,0.000420143,0.0002624144,0.005932859],"genre_scores_gemma":[0.9913335,0.0003890399,0.001877721,0.00008909012,0.00001322322,0.00002404134,0.0002945423,0.00009315451,0.005885576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002292352,"threshold_uncertainty_score":0.01152527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003742590355725264,"score_gpt":0.2076973957686659,"score_spread":0.2039548054129406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}