{"id":"W1996570113","doi":"10.1111/j.1348-0421.2009.00178.x","title":"Non-structural and nucleocapsid proteins of Punta Toro virus induce apoptosis of hepatocytes through both intrinsic and extrinsic pathways","year":2009,"lang":"en","type":"article","venue":"Microbiology and Immunology","topic":"Viral Infections and Vectors","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Nuclear Safety and Security Commission","keywords":"Apoptosis; Transfection; Biology; Bunyaviridae; Molecular biology; Phlebovirus; Caspase 3; Virus; Cell biology; Fas ligand; Inhibitor of apoptosis domain; Caspase; Hepatocyte; Virology; Gene; Biochemistry; Programmed cell death; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007149483,0.0001694993,0.0005165415,0.0001049732,0.00009179985,0.000004302668,0.00004690652,0.0002930672,0.00003637524],"category_scores_gemma":[0.00002726489,0.0001334563,0.00004351373,0.0001005546,0.0006506722,0.00008422524,0.00007500548,0.0002248913,0.00000125375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001969137,"about_ca_system_score_gemma":0.00003946848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003893934,"about_ca_topic_score_gemma":0.00002606995,"domain_scores_codex":[0.9991698,0.00005287521,0.0002998117,0.0002519953,0.00001670104,0.0002088614],"domain_scores_gemma":[0.9995706,0.00003486499,0.0001378826,0.0001764494,0.0000508859,0.00002932672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00028286,0.00005762664,0.01534275,0.00004219885,0.0001142303,0.000002227552,0.0005485547,4.964323e-8,0.9709846,0.000956527,0.00003025749,0.01163811],"study_design_scores_gemma":[0.001699295,0.003325978,0.2648887,0.00006312037,0.00007855411,0.0005901102,0.0001945185,0.000003240119,0.7279514,0.0004036856,0.000660301,0.0001411169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948417,0.004323802,0.00001448342,0.000188428,0.000110267,0.0003364196,0.0000263668,0.00001816481,0.0001403628],"genre_scores_gemma":[0.998086,0.001242065,0.0003978775,0.0001921744,0.00002773171,0.000006445313,0.00002017402,0.00000792854,0.00001961964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2495459,"threshold_uncertainty_score":0.5442191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01336901263919078,"score_gpt":0.2396457012012108,"score_spread":0.22627668856202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}