{"id":"W1996623626","doi":"10.1517/14712598.2012.668517","title":"Eculizumab for treatment of asthma","year":2012,"lang":"en","type":"review","venue":"Expert Opinion on Biological Therapy","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Eculizumab; Medicine; Asthma; Immunology; Paroxysmal nocturnal hemoglobinuria; Complement system; Exacerbation; Allergy; Monoclonal; Monoclonal antibody; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003492784,0.0006220989,0.0009685488,0.001263246,0.0001845725,0.0005349704,0.0006805864,0.001118144,0.005615556],"category_scores_gemma":[0.0004013792,0.0001388276,0.0004069263,0.0008120852,0.0002973892,0.0006208032,0.0004255919,0.001748839,0.003764863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004961665,"about_ca_system_score_gemma":0.0004503053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005577026,"about_ca_topic_score_gemma":0.001140843,"domain_scores_codex":[0.999832,0.00003682637,0.00001908096,0.00003171572,0.000062597,0.00001771705],"domain_scores_gemma":[0.9998742,0.00004518668,0.0000284963,0.000004605402,0.00002964729,0.00001776253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001069168,0.00005471754,0.0001065577,0.007709437,0.00007417063,0.0004050261,0.00002937748,0.000170334,0.002058582,0.002439943,0.05689317,0.9299517],"study_design_scores_gemma":[0.00006679283,0.00009423692,0.0006414251,0.002600713,0.00006898644,0.002963819,0.00002130438,0.00008154227,0.0005211682,0.001434279,0.991493,0.00001279407],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001297731,0.9966424,0.0001371182,0.0006145447,0.0004292504,0.000006838572,0.00001978863,0.000011187,0.002009068],"genre_scores_gemma":[0.001794765,0.9936766,0.0003251373,0.0009422777,0.0007197677,0.00001581952,0.00008061193,0.000003249525,0.002441736],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005615556,"threshold_uncertainty_score":0.01878595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3470602536935998,"score_gpt":0.4417960991504729,"score_spread":0.09473584545687308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}