{"id":"W1996645723","doi":"10.1016/j.tiv.2004.03.003","title":"Glycoprotein isolated from Solanum nigrum L. inhibits the DNA-binding activities of NF-κB and AP-1, and increases the production of nitric oxide in TPA-stimulated MCF-7 cells","year":2004,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"Phytochemical Studies and Bioactivities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Electrophoretic mobility shift assay; Western blot; Molecular biology; Nitric oxide; Cytotoxicity; NF-κB; Chemistry; Glycoprotein; Cell culture; Activator (genetics); MCF-7; Cancer cell; Receptor; Transcription factor; Biochemistry; Biology; In vitro; Apoptosis; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001845425,0.0001484922,0.0002609474,0.00006269545,0.00007357783,0.000007336581,0.0001063525,0.0001772473,0.000002382802],"category_scores_gemma":[0.0001494741,0.00009813204,0.00003439304,0.0001801567,0.0004553683,0.000008785297,0.0001822686,0.0001667293,2.45226e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002615825,"about_ca_system_score_gemma":0.00003420552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008668208,"about_ca_topic_score_gemma":0.0004147703,"domain_scores_codex":[0.9990975,0.0001059748,0.0002514803,0.0002579512,0.00007389893,0.0002132327],"domain_scores_gemma":[0.9995236,0.0001169201,0.0001462429,0.0001647544,0.00002513049,0.00002335897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000677332,0.0001673533,0.001457837,0.00002200849,0.00005219482,0.000001877695,0.0001399532,0.00004108104,0.9971313,0.000003249968,0.00006655485,0.000239201],"study_design_scores_gemma":[0.000692879,0.0001979733,0.00645552,0.00003806998,0.00002131591,0.000008403768,0.0006834108,0.00002017231,0.9914653,0.0002611114,0.00004995437,0.0001058443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981757,0.0008320077,0.00000596238,0.0003439391,0.0000359343,0.0003607473,0.0002275377,0.000004715635,0.00001344485],"genre_scores_gemma":[0.9994088,0.0002914639,0.00005367124,0.00006630573,0.00004224748,0.00003323343,0.00008339683,0.000007766623,0.00001306618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005666012,"threshold_uncertainty_score":0.4001709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006965507392015003,"score_gpt":0.214898024736632,"score_spread":0.207932517344617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}