{"id":"W1996677715","doi":"10.2310/7750.2012.12036","title":"One-Year, Multicenter, Open-Label, Single-Arm Study Evaluating the Safety and Effectiveness of Etanercept for the Treatment of Moderate-to-Severe Plaque Psoriasis in a Canadian Population","year":2013,"lang":"en","type":"article","venue":"Journal of Cutaneous Medicine and Surgery","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dermatrials Research; Hôpital de l'Enfant-Jésus; Institute of Cosmetic and Laser Surgery; Université Laval; Lynde Centre for Dermatology; Amgen (Canada); SKiN Health; University of British Columbia","funders":"Pfizer Canada; Amgen Canada; Amgen","keywords":"Medicine; Etanercept; Dermatology Life Quality Index; Psoriasis; Psoriasis Area and Severity Index; Adverse effect; Clinical endpoint; Plaque psoriasis; Internal medicine; Population; Quality of life (healthcare); Open label; Body surface area; Surgery; Randomized controlled trial; Dermatology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003344043,0.001062057,0.001493222,0.0003893148,0.001778675,0.0006222284,0.0009553541,0.0009083585,0.00228339],"category_scores_gemma":[0.002798278,0.0004420436,0.0009449701,0.0007358659,0.001381417,0.000425238,0.0003230048,0.001265028,0.0002881901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008255841,"about_ca_system_score_gemma":0.0123233,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.3623211,"about_ca_topic_score_gemma":0.4194507,"domain_scores_codex":[0.9987177,0.0003761115,0.00004887352,0.0001930559,0.000417988,0.0002462936],"domain_scores_gemma":[0.9976912,0.0003164547,0.0005622783,0.0001141833,0.0004862768,0.0008295475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4955024,0.05248264,0.3470798,0.001357096,0.003832839,0.0006225671,0.001522002,0.001639147,0.01682165,0.0002995986,0.005266826,0.0735735],"study_design_scores_gemma":[0.1207264,0.1279378,0.7418269,0.0000726686,0.001814504,0.0005330914,0.000371083,0.001980939,0.001822363,0.000110742,0.002658732,0.0001448291],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973608,0.0006340828,0.0001169514,0.0001316113,0.00001412834,0.0006239695,0.0005403079,0.00001089568,0.0005672483],"genre_scores_gemma":[0.9973493,0.0004433637,0.000541272,0.0002229604,0.0000504185,0.0002205559,0.0006535114,0.000003627131,0.0005150793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6376789,"threshold_uncertainty_score":0.7204243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07198932471620476,"score_gpt":0.3212766400322961,"score_spread":0.2492873153160913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}