{"id":"W1996705438","doi":"10.1016/j.neurobiolaging.2013.04.026","title":"Improvement of cognitive function and physical activity of aging mice by human neural stem cells over-expressing choline acetyltransferase","year":2013,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital","funders":"Ministry of Education, Science and Technology","keywords":"Choline acetyltransferase; Neurotrophin; Nerve growth factor; Neurotrophic factors; Cholinergic neuron; Neural stem cell; Cholinergic; Acetylcholine; Neuroscience; Brain-derived neurotrophic factor; Transplantation; Biology; Stem cell; Endocrinology; Internal medicine; Cell biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004782375,0.0001774297,0.000439606,0.00008413978,0.00005423171,0.000006007578,0.00004452389,0.00004479875,0.00001533996],"category_scores_gemma":[0.000009828416,0.0001551756,0.00009776838,0.00008099328,0.0002208904,0.0001502687,0.00004672144,0.0001752473,4.221186e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000661848,"about_ca_system_score_gemma":0.000016584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000842243,"about_ca_topic_score_gemma":0.000001309475,"domain_scores_codex":[0.9990647,0.00009553744,0.0002502107,0.0003187467,0.00009298611,0.0001777593],"domain_scores_gemma":[0.9992719,0.00020567,0.0001912896,0.0001245094,0.0001337746,0.00007291431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001365782,0.000498366,0.009201713,0.0002473748,0.00005810019,0.000001567209,0.0002562091,0.000008899591,0.9860326,0.000001689843,0.00004279432,0.003514125],"study_design_scores_gemma":[0.001866615,0.0007937988,0.0614876,0.0001845366,0.0002152297,0.00000353718,0.0001011811,0.0002794511,0.9349717,0.000004010238,0.0000014836,0.00009080832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991529,0.0001279731,0.00006656722,0.0001034216,0.00007138104,0.0003637604,0.00008004962,0.00001688942,0.00001702978],"genre_scores_gemma":[0.9995243,0.0000246662,0.000006496055,0.0002857115,0.00007320469,0.00001063,0.00003097433,0.00001745925,0.00002656451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05228589,"threshold_uncertainty_score":0.6327877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01875903104492209,"score_gpt":0.2826568643811914,"score_spread":0.2638978333362693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}