{"id":"W1996707491","doi":"10.1159/000020641","title":"Animal Models of Alport Syndrome: Advancing the Prospects for Effective Human Gene Therapy","year":2000,"lang":"en","type":"review","venue":"Nephron Experimental Nephrology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Alport syndrome; Disease; Genetic enhancement; Human disease; Medicine; Kidney disease; Animal model; Bioinformatics; Biology; Glomerulonephritis; Gene; Pathology; Kidney; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001750656,0.0009040271,0.001912786,0.001819497,0.0002548329,0.001418973,0.0011585,0.002097543,0.002372905],"category_scores_gemma":[0.0007372063,0.0003919504,0.0004642208,0.001155732,0.0009070586,0.002025225,0.000671537,0.002854654,0.001543546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006520657,"about_ca_system_score_gemma":0.0006665841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006366273,"about_ca_topic_score_gemma":0.0009896259,"domain_scores_codex":[0.9995328,0.0001381247,0.00004799333,0.000045247,0.0002044255,0.00003138756],"domain_scores_gemma":[0.9993572,0.0003773606,0.00006976975,0.00003423202,0.0001067015,0.00005469464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003386576,0.000284844,0.0007271942,0.01083035,0.0001658382,0.001435283,0.0001736775,0.001333782,0.0647444,0.0207873,0.02210567,0.877073],"study_design_scores_gemma":[0.00008393048,0.0005153072,0.001412546,0.002244192,0.000163237,0.004550156,0.000149797,0.0004602879,0.009517488,0.009444143,0.9714109,0.00004794745],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000894781,0.9927602,0.0029515,0.0007874155,0.0002023661,0.0000159435,0.00002264464,0.00003859923,0.002326561],"genre_scores_gemma":[0.002199265,0.9939374,0.002554995,0.0003465919,0.0001417816,0.00002048976,0.00003814322,0.000005765095,0.0007555813],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002372905,"threshold_uncertainty_score":0.009258509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01697510144230286,"score_gpt":0.3162918197808186,"score_spread":0.2993167183385158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}