{"id":"W1996715486","doi":"10.1038/tpj.2014.44","title":"N-acetyltransferase 1 polymorphism increases cotinine levels in Caucasian children exposed to secondhand smoke: the CCAAPS birth cohort","year":2014,"lang":"en","type":"article","venue":"The Pharmacogenomics Journal","topic":"Smoking Behavior and Cessation","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Environmental Health Sciences; National Institutes of Health","keywords":"Cotinine; Nicotine; Minor allele frequency; Secondhand smoke; Medicine; Single-nucleotide polymorphism; Physiology; Allele; SNP; Internal medicine; Genotype; Endocrinology; Biology; Genetics; Gene; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004080739,0.0006075157,0.0004339633,0.0006102619,0.0009103917,0.001029027,0.0006117845,0.0008576408,0.00300908],"category_scores_gemma":[0.001123571,0.0007599439,0.0009049803,0.0008628166,0.0003976387,0.0003266808,0.0005355719,0.001271238,0.0004443024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003592404,"about_ca_system_score_gemma":0.0006566397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04929197,"about_ca_topic_score_gemma":0.04171637,"domain_scores_codex":[0.9995446,0.00008899089,0.00002902101,0.0001603811,0.00007825434,0.00009870104],"domain_scores_gemma":[0.9989833,0.0001335478,0.0003350874,0.0001404917,0.0001220932,0.0002853921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003982134,0.00007710265,0.9950982,0.000008209919,0.0001557597,0.0003422971,0.0002634268,0.00002822296,0.002501068,0.00004927436,0.0001816268,0.0008965179],"study_design_scores_gemma":[0.000007180789,0.00006618058,0.9989665,0.000004100787,0.00007069828,0.0002925721,0.000223816,0.00005484391,0.0001333622,0.0000145685,0.0001618886,0.000004388502],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989389,0.0001580687,0.00005737669,0.00005504408,0.00001887327,0.000003290139,0.0003501142,0.000004968118,0.0004135137],"genre_scores_gemma":[0.9983833,0.0002232155,0.00007099372,0.00003172484,0.00001992098,0.000006903008,0.000301208,0.000009859383,0.0009529082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04929197,"threshold_uncertainty_score":0.09801012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0322616957324743,"score_gpt":0.297491707820423,"score_spread":0.2652300120879487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}