{"id":"W1996748544","doi":"10.1128/mcb.00636-06","title":"Transcriptional Regulation Is Affected by Subnuclear Targeting of Reporter Plasmids to PML Nuclear Bodies","year":2006,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Biology; Transactivation; Plasmid; Transcription (linguistics); Reporter gene; Molecular biology; Promoter; Transgene; DNA; Cell biology; Repressor; Luciferase; Coactivator; Transfection; Transcription factor; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001934575,0.0002293953,0.0002519663,0.0000671319,0.0001015137,0.00002142965,0.0001504154,0.0003091841,0.00008774181],"category_scores_gemma":[0.00003843667,0.000225592,0.0001275852,0.00009122059,0.0001938947,0.000005675407,0.00007999709,0.00008574021,0.000006423528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001166166,"about_ca_system_score_gemma":0.00003095829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005416412,"about_ca_topic_score_gemma":0.000003025095,"domain_scores_codex":[0.9985311,0.0001024143,0.000396831,0.0005399842,0.0001319608,0.000297694],"domain_scores_gemma":[0.999398,0.000006999638,0.000136687,0.0002636742,0.0001163026,0.00007834474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008142438,0.0000612329,0.0009334492,0.00004740522,0.00004952863,0.000006236945,0.00005581004,0.00002467819,0.9917409,0.0009859998,0.005716642,0.0002966803],"study_design_scores_gemma":[0.0003995179,0.0003524313,0.000416716,0.00001140674,0.00003354168,0.00001832038,0.00004113919,0.0000649437,0.927664,0.0005988365,0.07014278,0.0002564185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842304,0.002770338,0.01085365,0.0002011015,0.00009307815,0.0001899228,0.00004449101,0.00002238954,0.001594629],"genre_scores_gemma":[0.9967179,0.00006460176,0.001371694,0.0003586039,0.000102039,0.00001201105,0.0007353497,0.00004134383,0.0005964686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06442613,"threshold_uncertainty_score":0.9199376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002836416859189649,"score_gpt":0.1974700346839418,"score_spread":0.1946336178247521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}