{"id":"W1997036058","doi":"10.1002/hlca.200690066","title":"Synthesis of Glycaro‐1,5‐lactams and Tetrahydrotetrazolopyridine‐5‐carboxylates: Inhibitors of <i>β</i>‐<scp>D</scp>‐Glucuronidase and <i>α</i>‐<scp>L</scp>‐Iduronidase","year":2006,"lang":"en","type":"article","venue":"Helvetica Chimica Acta","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Lactam; Stereochemistry; Yield (engineering); Substrate (aquarium); Dihydroxylation; Organic chemistry; Enantioselective synthesis; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001714664,0.0004790798,0.0003706382,0.0001667545,0.0001020367,0.0001814934,0.0004229068,0.0003277002,0.001175395],"category_scores_gemma":[0.0001640676,0.0001726206,0.0002505047,0.0002587953,0.0001308937,0.0002199664,0.0001908903,0.0004465948,0.0008742723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004865034,"about_ca_system_score_gemma":0.0005268779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000877324,"about_ca_topic_score_gemma":0.001188198,"domain_scores_codex":[0.9998375,0.00002359687,0.00001931042,0.00002729868,0.00003721617,0.00005504812],"domain_scores_gemma":[0.9999127,0.000006452237,0.00002361035,0.00001009412,0.00001644884,0.00003069554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001181513,0.00004725123,0.00007403967,0.0001588235,0.00001758189,0.0001486131,0.0000363499,0.0005346798,0.9930507,0.000574702,0.0002951265,0.004943929],"study_design_scores_gemma":[0.00005428315,0.0004758936,0.0005480867,0.000008363374,0.00002109314,0.0002612229,0.0000133333,0.001008288,0.9895276,0.00005845126,0.008006768,0.00001651494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9526822,0.008143255,0.02232118,0.0003211967,0.0002586415,0.0003813251,0.002008592,0.0005710382,0.01331268],"genre_scores_gemma":[0.9703845,0.004472782,0.01679752,0.0001059395,0.0000253495,0.0001932318,0.001114853,0.00006718066,0.006838745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001175395,"threshold_uncertainty_score":0.003932118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006092034813855987,"score_gpt":0.1939551156028705,"score_spread":0.1878630807890146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}