{"id":"W1997057308","doi":"10.1016/j.imbio.2012.10.002","title":"A novel role of the scaffolding protein JLP in tuning CD40-induced activation of dendritic cells","year":2012,"lang":"en","type":"article","venue":"Immunobiology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Manitoba Medical Service Foundation; Manitoba Health Research Council","keywords":"Internalization; Cell biology; Scaffold protein; CD40; MAPK/ERK pathway; Receptor; Signal transduction; Signal transducing adaptor protein; Biology; Chemistry; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006141237,0.0001932822,0.0004259144,0.0002137523,0.0001113873,0.000003480404,0.0004182578,0.0003748907,0.0001581878],"category_scores_gemma":[0.0001724933,0.0001478839,0.0001461091,0.0003200862,0.0002973844,0.0001670957,0.0001468403,0.0003389211,0.00002930595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005992299,"about_ca_system_score_gemma":0.00009379443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006367661,"about_ca_topic_score_gemma":0.000008542322,"domain_scores_codex":[0.9981404,0.0005607164,0.0005886495,0.0001723849,0.00003307463,0.0005047629],"domain_scores_gemma":[0.9987929,0.0003113907,0.0003744314,0.0004429164,0.00006982093,0.000008533339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004835784,0.0003176398,0.002901033,0.00002087202,0.000116904,7.336037e-8,0.001496761,0.000004038853,0.9894865,0.001069932,0.000005312489,0.004097341],"study_design_scores_gemma":[0.001304689,0.0001789819,0.03258443,0.0001897557,0.00001534408,0.00003271848,0.0009151109,0.000002402052,0.9629916,0.00005404969,0.001587343,0.0001435689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921429,0.00639152,0.00006046314,0.00005598488,0.0006199125,0.0004567616,0.00001046882,0.00001798636,0.000244015],"genre_scores_gemma":[0.9994611,0.00003976467,0.00009368554,0.00004078684,0.00001644407,0.00004553037,0.00001279613,0.00002057284,0.0002693227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02968339,"threshold_uncertainty_score":0.6030529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01503010132882842,"score_gpt":0.236799342532025,"score_spread":0.2217692412031965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}