{"id":"W1997065380","doi":"10.1021/la1014829","title":"pH-Triggered Release from Nonphospholipid LUVs Modulated by the p<i>K</i><sub>a</sub> of the Included Fatty Acid","year":2010,"lang":"en","type":"article","venue":"Langmuir","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Protonation; Vesicle; Fatty acid; Deprotonation; Palmitic acid; Sterol; Membrane; Liposome; Chromatography; Biophysics; Cholesterol; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009793165,0.0001949523,0.0001834412,0.00001272063,0.0001502139,0.00001999661,0.0005355285,0.000264395,0.00004266568],"category_scores_gemma":[0.00006223994,0.0001097451,0.0001668352,0.0001322537,0.0001702224,0.000004567927,0.000219579,0.0002890967,0.00001261322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005964414,"about_ca_system_score_gemma":0.00005101221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001708113,"about_ca_topic_score_gemma":0.0001693839,"domain_scores_codex":[0.998962,0.00006449068,0.0002298103,0.0003073131,0.0001970264,0.0002393848],"domain_scores_gemma":[0.9989175,0.00001552828,0.0001486014,0.0007766119,0.00007778073,0.00006403212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006226221,0.00004759068,0.001422917,0.000006532022,0.00003981651,9.354537e-7,0.00008323971,0.000001363584,0.9907457,0.00000991779,0.005011554,0.002568231],"study_design_scores_gemma":[0.0006015007,0.00003186027,0.01967357,0.000005440229,0.00006119867,0.000009587926,0.00002145792,0.000009377532,0.9636347,0.00003185801,0.01576656,0.000152851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978772,0.0001676292,0.00002839906,0.0004065018,0.0006785215,0.0002352261,0.0003145521,0.00001884247,0.0002731437],"genre_scores_gemma":[0.9983023,0.00002731809,0.00006750494,0.0006173487,0.0004797724,0.00001877095,0.0003183782,0.00002887483,0.0001397562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0271109,"threshold_uncertainty_score":0.4475276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004140067109266982,"score_gpt":0.2048628875430129,"score_spread":0.2007228204337459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}