{"id":"W1997071370","doi":"10.1046/j.1471-4159.2001.00174.x","title":"Oxidative post‐translational modifications of α‐synuclein in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) mouse model of Parkinson's disease","year":2001,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":190,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Movement Disorders","funders":"National Institutes of Health; ALS Association; International Society for Neurochemistry; U.S. Department of Defense","keywords":"MPTP; Alpha-synuclein; Neurodegeneration; Parkinson's disease; Neurotoxin; Chemistry; Neuroprotection; Dopaminergic; Pharmacology; Biology; Neuroscience; Biochemistry; Internal medicine; Dopamine; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002033458,0.0001783223,0.0003687174,0.0001452954,0.00004075719,0.000008674363,0.0002544571,0.00006330149,0.00005568728],"category_scores_gemma":[0.0002215554,0.0001309613,0.0002805578,0.0002628957,0.00009252077,0.0001260724,0.00001841178,0.0002710703,0.000001297086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003704809,"about_ca_system_score_gemma":0.0002983186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006134525,"about_ca_topic_score_gemma":8.42637e-7,"domain_scores_codex":[0.9983339,0.00005985018,0.0006317888,0.0001832315,0.0006180615,0.0001731101],"domain_scores_gemma":[0.9984625,0.0001242967,0.0005172995,0.0003299555,0.0003513903,0.0002145456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001346143,0.00210201,0.00659282,0.0001311414,0.0001426078,0.0002124795,0.0003004634,0.002770223,0.9857577,0.0001133972,0.0001210028,0.0004099937],"study_design_scores_gemma":[0.01168667,0.0009592547,0.3897766,0.0006323851,0.001793235,0.0005290983,0.0009393793,0.04771823,0.539767,0.003560786,0.002094381,0.0005429563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964433,0.0004091779,0.0008210616,0.00144048,0.00002571144,0.0001666611,0.0001883731,0.000005932255,0.0004992794],"genre_scores_gemma":[0.9981372,0.0002893564,0.001155714,0.0001712684,0.00006024375,0.000007012724,0.00002921958,0.00001970991,0.0001302386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4459907,"threshold_uncertainty_score":0.5340447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03014990413414472,"score_gpt":0.2786842559797229,"score_spread":0.2485343518455781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}