{"id":"W1997071370","doi":"10.1046/j.1471-4159.2001.00174.x","title":"Oxidative post‐translational modifications of α‐synuclein in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) mouse model of Parkinson's disease","year":2001,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":190,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Movement Disorders","funders":"National Institutes of Health; ALS Association; International Society for Neurochemistry; U.S. Department of Defense","keywords":"MPTP; Alpha-synuclein; Neurodegeneration; Parkinson's disease; Neurotoxin; Chemistry; Neuroprotection; Dopaminergic; Pharmacology; Biology; Neuroscience; Biochemistry; Internal medicine; Dopamine; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002032911,0.0004689347,0.0002550684,0.0004001124,0.0002271332,0.0002544558,0.0001491688,0.0005104683,0.0008199715],"category_scores_gemma":[0.0001125638,0.0003178035,0.0002824493,0.0001470934,0.0002013928,0.0002272027,0.0001339034,0.0005174599,0.0002581654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002838487,"about_ca_system_score_gemma":0.000114571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005043037,"about_ca_topic_score_gemma":0.0009896208,"domain_scores_codex":[0.9998801,0.00002933368,0.00001115235,0.0000224752,0.00003025476,0.00002658994],"domain_scores_gemma":[0.9998953,0.00001009447,0.0000401041,0.00001118416,0.000009568507,0.0000337723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002531139,0.00007118261,0.0002529775,0.00002148185,0.000007534794,0.0001510797,0.00001496653,0.00003224043,0.9987215,0.00006805085,0.00003097334,0.0003748228],"study_design_scores_gemma":[0.00008790862,0.001443113,0.02322869,0.00001573185,0.00006398612,0.001756376,0.00005692112,0.001760867,0.9703031,0.0002305627,0.001045371,0.000007374347],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976801,0.0007612788,0.0007641016,0.00006805623,0.0000168014,0.00001787132,0.0001114021,0.00004116293,0.0005392003],"genre_scores_gemma":[0.9954509,0.0008686443,0.001178273,0.00004348052,0.0000111142,0.00003327354,0.000312043,0.00001261825,0.002089658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008199715,"threshold_uncertainty_score":0.002743125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03014990413414472,"score_gpt":0.2786842559797229,"score_spread":0.2485343518455781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}