{"id":"W1997096528","doi":"10.1021/bi0491245","title":"Detection of TAP Family Dimerizations by an<i>in Vivo</i>Assay in Mammalian Cells","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Transporter associated with antigen processing; Protein-fragment complementation assay; ATP-binding cassette transporter; In vivo; Transporter; Chinese hamster ovary cell; Complementation; Biology; Biochemistry; Cell biology; Molecular biology; Chemistry; In vitro; Gene; Antigen presentation; Genetics; Phenotype; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008388209,0.00009487574,0.0001543937,0.00004729038,0.00001532797,0.000003180882,0.00005652082,0.000132658,0.00002935864],"category_scores_gemma":[0.000006885129,0.00009394834,0.00003947979,0.0002381518,0.00003982999,0.00002902443,0.000004311225,0.0001021107,0.000002398847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000655992,"about_ca_system_score_gemma":0.00007327961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001436663,"about_ca_topic_score_gemma":0.00007001885,"domain_scores_codex":[0.9993115,0.000006984984,0.0002180076,0.0001858234,0.0001312337,0.0001464462],"domain_scores_gemma":[0.9996752,0.000004575318,0.00004635719,0.0001789567,0.00002439997,0.00007048339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004255912,0.0002733752,0.001008016,0.0001045589,0.000003853153,0.0000220204,0.00006481,0.00002642231,0.9982098,0.000007704174,0.00002280695,0.0002141252],"study_design_scores_gemma":[0.001014585,0.00003959176,0.002271645,0.0001002532,0.00001588844,0.000003012112,0.0002334664,0.00001604853,0.9958229,0.00003232431,0.0003588135,0.00009144399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966865,0.0002453141,0.001487948,0.00006084779,0.00007843882,0.0001364274,0.00003529246,0.00002198086,0.001247286],"genre_scores_gemma":[0.9986224,0.00004051019,0.0004600661,0.00005481403,0.00003121346,0.00001710664,0.0000552592,0.00001397529,0.0007046126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002386821,"threshold_uncertainty_score":0.3831102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005598667319783771,"score_gpt":0.2159462512247592,"score_spread":0.2103475839049754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}