{"id":"W1997096528","doi":"10.1021/bi0491245","title":"Detection of TAP Family Dimerizations by an<i>in Vivo</i>Assay in Mammalian Cells","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Transporter associated with antigen processing; Protein-fragment complementation assay; ATP-binding cassette transporter; In vivo; Transporter; Chinese hamster ovary cell; Complementation; Biology; Biochemistry; Cell biology; Molecular biology; Chemistry; In vitro; Gene; Antigen presentation; Genetics; Phenotype; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00100968,0.0009010736,0.0007053084,0.0005027981,0.0006130738,0.0008037362,0.000971087,0.0007537003,0.002200705],"category_scores_gemma":[0.0005915505,0.0005413319,0.0006593092,0.0006160951,0.0004425396,0.0005022563,0.0006639413,0.001625342,0.002649906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005737251,"about_ca_system_score_gemma":0.00022725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001012208,"about_ca_topic_score_gemma":0.001027339,"domain_scores_codex":[0.9984223,0.0007086888,0.0001099173,0.0003510357,0.0002853532,0.0001227408],"domain_scores_gemma":[0.9992985,0.0002459309,0.0001174613,0.000131908,0.0001394089,0.00006681127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002695238,0.000019893,0.0000590088,0.00002383505,0.000004198178,0.00001494517,0.00002458333,0.00001979822,0.9991836,0.00007327156,0.00006610456,0.0004838016],"study_design_scores_gemma":[0.000007938756,0.0001078415,0.0009737641,0.000003577902,0.00001320418,0.0001472661,0.00002425146,0.0013115,0.9952464,0.00004932608,0.002108573,0.000006467867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6657953,0.006708434,0.3055561,0.0008914003,0.0002555249,0.0004554286,0.003600336,0.002398286,0.01433925],"genre_scores_gemma":[0.7998627,0.006545186,0.1654268,0.000530338,0.0001788191,0.001139231,0.007567843,0.0007017708,0.01804719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002200705,"threshold_uncertainty_score":0.007362068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005598667319783771,"score_gpt":0.2159462512247592,"score_spread":0.2103475839049754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}