{"id":"W1997136944","doi":"10.1038/sj.gt.3302075","title":"Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Alkaline phosphatase; Recombinant DNA; Viral vector; Bone morphogenetic protein 2; Bone morphogenetic protein; Bone morphogenetic protein 7; In vivo; In vitro; Human bone; Genetic enhancement; Molecular biology; Bone morphogenetic protein 6; Adenoviridae; Biology; Chemistry; Biochemistry; Enzyme; Biotechnology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002222749,0.0001936719,0.0001881584,0.00005125474,0.00008949271,0.00001606407,0.000289819,0.0001015118,0.00006318084],"category_scores_gemma":[0.00002373236,0.0001394327,0.0001410261,0.00009254214,0.00008712517,0.000001931448,0.00003228308,0.00009748154,0.000003774373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001431542,"about_ca_system_score_gemma":0.00006595415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002209208,"about_ca_topic_score_gemma":0.00002436031,"domain_scores_codex":[0.9985753,0.0003845659,0.0002924184,0.000299831,0.0001847253,0.0002632009],"domain_scores_gemma":[0.9993159,0.000008321778,0.0001152901,0.0004781475,0.00003798284,0.00004433754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000151948,0.0002913415,0.0009799866,0.000008988876,0.00004291507,0.00000869587,0.0001516024,0.0001084679,0.9974453,0.00001924766,0.00008343589,0.0007080279],"study_design_scores_gemma":[0.00143144,0.0006624064,0.01055469,0.00001334198,0.00001330018,0.00001332677,0.00009285784,0.000003790879,0.986155,0.0001749198,0.000705629,0.0001793266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934126,0.005785847,0.00004407141,0.0000308495,0.000128972,0.000551105,0.000008304,0.000006914197,0.00003137369],"genre_scores_gemma":[0.9991671,0.0001314954,0.00008744084,0.00008206147,0.00007750092,0.0001014172,0.00006632078,0.00002849055,0.000258144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01129037,"threshold_uncertainty_score":0.5685902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009944467905602968,"score_gpt":0.2362199727552582,"score_spread":0.2262755048496552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}