{"id":"W1997136944","doi":"10.1038/sj.gt.3302075","title":"Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Alkaline phosphatase; Recombinant DNA; Viral vector; Bone morphogenetic protein 2; Bone morphogenetic protein; Bone morphogenetic protein 7; In vivo; In vitro; Human bone; Genetic enhancement; Molecular biology; Bone morphogenetic protein 6; Adenoviridae; Biology; Chemistry; Biochemistry; Enzyme; Biotechnology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000629933,0.0004019383,0.0003332855,0.0008370604,0.0002262401,0.0005303912,0.0002978854,0.0004173291,0.0007491165],"category_scores_gemma":[0.0003827301,0.0002145096,0.0003354716,0.0003852061,0.000525201,0.0004386272,0.0002238443,0.0005125407,0.0001542976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004419264,"about_ca_system_score_gemma":0.0005838547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001295774,"about_ca_topic_score_gemma":0.001157196,"domain_scores_codex":[0.9996474,0.00005235332,0.00005151517,0.00005146965,0.00009916285,0.00009812158],"domain_scores_gemma":[0.9996426,0.0001147984,0.00008209498,0.00003204964,0.00004567932,0.00008281219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005929543,0.00009615785,0.0003373057,0.00005998291,0.00001262407,0.00004069433,0.00004843913,0.0002408916,0.9937122,0.0008698815,0.00002902604,0.003959752],"study_design_scores_gemma":[0.00003373576,0.0007560788,0.0008737195,0.00001108742,0.00008058947,0.0000991188,0.00004458832,0.0008341862,0.9961007,0.0001402162,0.001016486,0.00000945473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946147,0.00183262,0.002292199,0.00006814184,0.00003821489,0.00002209254,0.0001446164,0.00003670502,0.0009507419],"genre_scores_gemma":[0.9923779,0.001475046,0.00312939,0.00002839264,0.00001118414,0.00002575838,0.0003245705,0.00002513037,0.002602642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001295774,"threshold_uncertainty_score":0.003331423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009944467905602968,"score_gpt":0.2362199727552582,"score_spread":0.2262755048496552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}