{"id":"W1997158650","doi":"10.1073/pnas.1100667108","title":"Regulation of type 17 helper T-cell function by nitric oxide during inflammation","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust","keywords":"Aryl hydrocarbon receptor; Experimental autoimmune encephalomyelitis; Nitric oxide; Inflammation; Immunology; Nitric oxide synthase; Autoimmune disease; Interleukin 17; Receptor; Autoimmunity; Pathogenesis; Chemistry; T cell; Biology; Cell biology; Immune system; Endocrinology; Biochemistry; Transcription factor; Antibody; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000415735,0.00006563504,0.0001028325,0.0001460217,0.0001258975,0.000002741663,0.0002166879,0.0001135004,0.00007547763],"category_scores_gemma":[0.00008623108,0.00004561493,0.00004592798,0.0004445814,0.0002551609,0.0002797219,0.00003768612,0.00005703207,0.000006742122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001749995,"about_ca_system_score_gemma":0.00001399465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000946793,"about_ca_topic_score_gemma":3.681145e-8,"domain_scores_codex":[0.9993873,0.000009660081,0.0002443871,0.0001282316,0.000143791,0.00008661937],"domain_scores_gemma":[0.9993221,0.00003497685,0.0004192545,0.00000737547,0.0002100469,0.000006251752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009346466,0.00003827499,0.01293547,0.00002785162,0.00002377371,5.444469e-10,0.0001284093,0.000006186866,0.9841704,0.001775661,0.0003940413,0.0004064768],"study_design_scores_gemma":[0.0002006544,0.00003168557,0.3220764,0.00001755459,0.00002483235,0.000001509778,0.00005921745,0.000006198673,0.6748583,0.002628214,0.00006435481,0.00003106238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941385,0.0003851051,7.836242e-7,0.00006069581,0.0000300005,0.0001041808,0.000007706827,0.000008499482,0.005264542],"genre_scores_gemma":[0.9985094,0.00003422478,0.0001661232,0.00001101705,0.00001597462,0.000004575687,0.000001439552,0.000002397366,0.001254815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3093121,"threshold_uncertainty_score":0.1860123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03306215582147709,"score_gpt":0.237140798473385,"score_spread":0.2040786426519079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}