{"id":"W1997283150","doi":"10.1038/embor.2012.17","title":"TCR‐mediated Erk activation does not depend on Sos and Grb2 in peripheral human T cells","year":2012,"lang":"en","type":"article","venue":"EMBO Reports","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Medizinischen Hochschule Hannover; Deutsche Forschungsgemeinschaft; Cochlear","keywords":"T-cell receptor; MAPK/ERK pathway; GRB2; Cell biology; Activator (genetics); Biology; T cell; Guanine nucleotide exchange factor; Signal transduction; Receptor; Genetics; Signal transducing adaptor protein; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000171732,0.0002322099,0.0002175784,0.0003473138,0.0002661945,0.0005468547,0.000245902,0.0002604999,0.006028343],"category_scores_gemma":[0.0003467084,0.000256024,0.0002267325,0.0002723932,0.0002245234,0.0003193683,0.0002679857,0.0006823448,0.00137738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001412376,"about_ca_system_score_gemma":0.0002204316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005210204,"about_ca_topic_score_gemma":0.0005226528,"domain_scores_codex":[0.9998019,0.00003978037,0.00001397592,0.00004263746,0.00002824775,0.00007347818],"domain_scores_gemma":[0.999795,0.0000508312,0.00002557894,0.00005929828,0.00001982621,0.00004946361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004295011,0.0002536404,0.004314973,0.00009883159,0.00002313962,0.0004359378,0.0001034816,0.0001125793,0.9828655,0.0002722659,0.0003197121,0.006904978],"study_design_scores_gemma":[0.0005118443,0.001767485,0.1433784,0.00003984387,0.0001307672,0.006262895,0.0003750421,0.002104088,0.8388118,0.0005838882,0.006007396,0.00002660702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967284,0.0008265831,0.0004698135,0.00004007691,0.00001302194,0.00001250748,0.0003113245,0.00004157645,0.00155669],"genre_scores_gemma":[0.9968234,0.0003133006,0.0002624787,0.00002175273,0.00001211006,0.00001996946,0.0008684006,0.00001645533,0.00166203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006028343,"threshold_uncertainty_score":0.02016687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01267152784186398,"score_gpt":0.2360891947847769,"score_spread":0.2234176669429129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}