{"id":"W1997289391","doi":"10.1021/ol702376j","title":"Total Synthesis of (±)-Goniomitine via a Formal Nitrile/Donor−Acceptor Cyclopropane [3 + 2] Cyclization","year":2007,"lang":"en","type":"article","venue":"Organic Letters","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Nitrile; Cyclopropane; Chemistry; Total synthesis; Yield (engineering); Cycloaddition; Acceptor; Indole test; Combinatorial chemistry; Ring (chemistry); Stereochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001352599,0.0005085296,0.0002971842,0.0002283869,0.0002152708,0.0003003537,0.0003502606,0.000192574,0.002396071],"category_scores_gemma":[0.000149718,0.0001393332,0.0002233201,0.0001395084,0.0002484202,0.00022438,0.00043152,0.0003779501,0.0006762819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003027811,"about_ca_system_score_gemma":0.0005791274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000356336,"about_ca_topic_score_gemma":0.00072897,"domain_scores_codex":[0.9999022,0.00001062637,0.0000112823,0.00001973198,0.00002372436,0.00003231217],"domain_scores_gemma":[0.9999316,0.000008305559,0.0000176349,0.00001298469,0.00001040883,0.00001917008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001052337,0.00004489864,0.0001152548,0.0002203261,0.00001973733,0.0003942076,0.00007369689,0.0005493138,0.9824085,0.001712687,0.0001470982,0.01420907],"study_design_scores_gemma":[0.0000415452,0.0005911697,0.0008586625,0.00001878812,0.00002926825,0.0006107218,0.00002418655,0.0004664124,0.9846208,0.0002870224,0.01243238,0.00001903486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9447988,0.002319279,0.02640981,0.0001627274,0.0001313536,0.0003282138,0.0008617844,0.00041935,0.0245687],"genre_scores_gemma":[0.9766192,0.001584761,0.01481747,0.00005494613,0.00001849119,0.0001401442,0.0004270489,0.00006663565,0.006271262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002396071,"threshold_uncertainty_score":0.008015692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004772313165975928,"score_gpt":0.1993164241221354,"score_spread":0.1945441109561595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}