{"id":"W1997312624","doi":"10.1155/2012/951574","title":"Role of<mml:math xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" id=\"M1\"><mml:mrow><mml:msup><mml:mtext>p16</mml:mtext><mml:mrow><mml:mtext>INK4A</mml:mtext></mml:mrow></mml:msup></mml:mrow></mml:math>in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells","year":2012,"lang":"en","type":"article","venue":"Biochemistry Research International","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Cancer Society; Alberta Cancer Foundation","keywords":"Computer science; Algorithm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002172847,0.000568979,0.00033045,0.0004797842,0.0005941681,0.0004428962,0.001552491,0.001311228,0.02637386],"category_scores_gemma":[0.002131609,0.0008772542,0.0005698802,0.0009024852,0.001338213,0.0007356246,0.001263505,0.001649597,0.0003705317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005874816,"about_ca_system_score_gemma":0.001224398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009758224,"about_ca_topic_score_gemma":0.0002932629,"domain_scores_codex":[0.9926261,0.0002633836,0.001274774,0.001515016,0.002581623,0.001739109],"domain_scores_gemma":[0.9951476,0.001028727,0.0008631326,0.001710437,0.0004174218,0.0008327079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001596787,0.0007827553,0.0003842238,0.001601319,0.0004872462,0.0005611691,0.002730785,0.00007976752,0.5789872,0.389708,0.02106712,0.002013706],"study_design_scores_gemma":[0.001558144,0.0006546447,0.00210734,0.001317435,0.0001556011,0.0006741068,0.002705383,0.04862839,0.9399902,0.00003153235,0.001482765,0.0006944143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8738436,0.001066595,0.0001088419,0.000766002,0.0006052678,0.0001018407,0.0002388255,0.00008981034,0.1231793],"genre_scores_gemma":[0.994273,0.0005283735,0.001126181,0.0003274801,0.001217646,0.0007359266,0.0008158557,0.000236699,0.0007388567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3896764,"threshold_uncertainty_score":0.9999853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03112264878304502,"score_gpt":0.3044371718469824,"score_spread":0.2733145230639374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}