{"id":"W1997356814","doi":"10.1016/j.schres.2011.03.032","title":"Genetic inactivation of GSK3α rescues spine deficits in Disc1-L100P mutant mice","year":2011,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"DISC1; Mutant; GSK-3; Neurite; Dendritic spine; Biology; Wild type; Cell biology; Gene; Genetics; Neuroscience; Signal transduction; Hippocampal formation; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002133663,0.001644838,0.0006244072,0.001791697,0.0005073558,0.0005891717,0.0008090787,0.001023566,0.004276157],"category_scores_gemma":[0.0003041963,0.0006525863,0.0005803787,0.000454102,0.001186672,0.0003555777,0.0006424914,0.001608134,0.001502939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00083992,"about_ca_system_score_gemma":0.0007658858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003883776,"about_ca_topic_score_gemma":0.007389386,"domain_scores_codex":[0.9997057,0.00002590161,0.00004913316,0.00006621843,0.00009969597,0.00005331676],"domain_scores_gemma":[0.999383,0.00005757232,0.0002694566,0.00004818911,0.00003340726,0.0002083707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001322422,0.00002452881,0.0001325216,0.00003210564,0.00001183369,0.0002860663,0.00002020317,0.00009542506,0.9983444,0.0001580029,0.00009877073,0.0006639247],"study_design_scores_gemma":[0.000175439,0.0001522494,0.00725397,0.00004285669,0.00007985552,0.001890584,0.0001439546,0.002084277,0.9851828,0.0003576089,0.002612489,0.00002390074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837167,0.001000648,0.00697855,0.0007378771,0.000176401,0.00006303944,0.003754221,0.0008351596,0.002737386],"genre_scores_gemma":[0.9846336,0.001055494,0.004867881,0.000145402,0.00002533624,0.00008766017,0.001258992,0.0004510197,0.007474637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004276157,"threshold_uncertainty_score":0.01430517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05029508767919941,"score_gpt":0.31127194193142,"score_spread":0.2609768542522206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}