{"id":"W1997499134","doi":"10.3109/1061186x.2010.499463","title":"Active targeting of dendritic cells with mannan-decorated PLGA nanoparticles","year":2010,"lang":"en","type":"article","venue":"Journal of drug targeting","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"PLGA; Nanoparticle; Chemistry; Covalent bond; Zeta potential; Adsorption; Polymer; Mannan; Drug delivery; Dispersity; Microparticle; Nanocarriers; Dendrimer; Chemical engineering; Drug carrier; Nanotechnology; Polymer chemistry; Materials science; Polysaccharide; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001566123,0.0002989165,0.0002636988,0.0001108168,0.0001026534,0.0003009355,0.0001600923,0.0002994261,0.0002664858],"category_scores_gemma":[0.0001563047,0.0001166405,0.0001564035,0.00007419189,0.0001838046,0.0002323084,0.0001799757,0.0002714001,0.0002185177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002870992,"about_ca_system_score_gemma":0.0001972958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002472249,"about_ca_topic_score_gemma":0.0004798856,"domain_scores_codex":[0.9999015,0.00002122183,0.000008455954,0.00002251292,0.0000272594,0.00001895156],"domain_scores_gemma":[0.9999347,0.00001568213,0.00001882058,0.000007008467,0.00001290359,0.00001092471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002765515,0.0000110078,0.00005213778,0.000022763,0.000001292866,0.00002009284,0.000006036687,0.00009761367,0.9989271,0.00003252289,0.000006577875,0.0007951473],"study_design_scores_gemma":[0.00001078902,0.0001353431,0.0003006236,0.000002890862,0.000008711657,0.00007384599,0.00000722343,0.001084973,0.9975311,0.00002019461,0.0008220363,0.00000224179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893306,0.0009627611,0.008961242,0.00008257844,0.00001443805,0.00004088397,0.00004037164,0.00003764645,0.000529527],"genre_scores_gemma":[0.983273,0.0006431353,0.01465103,0.00006806841,0.00001777021,0.00004236754,0.0001139825,0.00002145805,0.00116914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003009355,"threshold_uncertainty_score":0.002083063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005440179326229547,"score_gpt":0.2196601405889244,"score_spread":0.2142199612626948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}