{"id":"W1997514113","doi":"10.4161/mabs.28421","title":"Antibody Engineering and Therapeutics","year":2014,"lang":"en","type":"article","venue":"mAbs","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Antibody; Computational biology; Immunotherapy; Antibody-drug conjugate; Bispecific antibody; Antibody Repertoire; Biology; Immunology; Monoclonal antibody; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008424826,0.00005428326,0.00009282266,0.00003598564,0.00002847084,0.00001040393,0.00002638946,0.00002742595,0.00005809491],"category_scores_gemma":[0.00001844767,0.00003971437,0.00002176422,0.00004399492,0.00002568883,0.00001490964,0.00002785902,0.00009519983,0.00004520618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004462949,"about_ca_system_score_gemma":0.000006804951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001672044,"about_ca_topic_score_gemma":6.999294e-7,"domain_scores_codex":[0.9996054,0.000007413376,0.00005935663,0.00008441488,0.0001134308,0.0001300286],"domain_scores_gemma":[0.9997739,0.00004437386,0.000006851294,0.00008172285,0.00002304828,0.00007009967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002291684,0.000105889,0.1880188,0.0004850808,0.0001501009,0.0000522519,0.000366558,0.0000117086,0.6882847,0.01952624,0.0004587107,0.1023108],"study_design_scores_gemma":[0.000607296,0.0002718066,0.2808818,0.00006030936,0.00002632114,0.0001131669,0.00001667911,0.01673978,0.004656177,0.0002275744,0.6962792,0.0001199438],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886343,0.0005054571,0.0007343095,0.002535097,0.0000545842,0.00006682298,0.000001383925,0.00003463961,0.007433346],"genre_scores_gemma":[0.9960823,0.0001736444,0.0007351945,0.0005960587,0.0001705274,0.000001616854,0.00001289206,0.000008802607,0.002218977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6958205,"threshold_uncertainty_score":0.1619505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01888505635754565,"score_gpt":0.3134748275983281,"score_spread":0.2945897712407824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}